SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4fur UREASE SUBUNIT GAMMA
2
(Brucella
abortus) 		3 / 3 ASP A  71
ASP A  75
ASP A  67
 None
 0.76A 2igtA-4furA:
undetectable		 2igtA-4furA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4fur UREASE SUBUNIT GAMMA
2
(Brucella
abortus) 		3 / 3 ASP A  71
ASP A  75
ASP A  67
 None
 0.76A 2igtB-4furA:
undetectable		 2igtB-4furA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 4fur UREASE SUBUNIT GAMMA
2
(Brucella
abortus) 		4 / 7 ASP A  88
SER A  87
GLU A  55
ASP A  58
 None
 1.23A 3bc9A-4furA:
undetectable		 3bc9A-4furA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4fur UREASE SUBUNIT GAMMA
2
(Brucella
abortus) 		4 / 4 LEU A  16
VAL A  19
GLU A  34
ARG A  23
 None
None
None
CL  A 203 (-3.5A)
 0.68A 4ww7A-4furA:
undetectable		 4ww7A-4furA:
16.22