SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DPZ_A_TYLA2001_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	4fuv	PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE (Acinetobacter baumannii)	4 / 6	LEU A 214 ALA A 102 ASP A 107 TYR A 108	None None None C8E A 303 ( 4.4A)	1.14A	2dpzA-4fuvA: undetectable	2dpzA-4fuvA: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PFG_A_SAMA264_1 (N-METHYLTRANSFERASE)	4fuv	PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE (Acinetobacter baumannii)	3 / 3	TYR A 76 TYR A 171 GLU A 80	None	0.98A	3pfgA-4fuvA: 3.2	3pfgA-4fuvA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_C_SUEC1201_2 (NS3 PROTEASE, NS4A PROTEIN)	4fuv	PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE (Acinetobacter baumannii)	4 / 5	TYR A 41 ILE A 17 LEU A 16 LYS A 13	None C8E A 308 ( 4.9A) C8E A 308 (-4.8A) None	1.16A	3sueC-4fuvA: undetectable	3sueC-4fuvA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	4fuv	PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE (Acinetobacter baumannii)	4 / 8	GLN A 125 THR A 188 VAL A 187 SER A 119	None	1.03A	6fbvC-4fuvA: undetectable	6fbvC-4fuvA: 12.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DPZ_A_TYLA2001_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","4fuv","PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE","Acinetobacter baumannii",4,"LEU A 214;ALA A 102;ASP A 107;TYR A 108","None;None;None;C8E A 303 ( 4.4A)","1.14A","2dpzA-4fuvA:undetectable","2dpzA-4fuvA:17.80"],["3PFG_A_SAMA264_1","N-METHYLTRANSFERASE","4fuv","PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE","Acinetobacter baumannii",3,"TYR A  76;TYR A 171;GLU A  80","None","0.98A","3pfgA-4fuvA:3.2","3pfgA-4fuvA:22.34"],["3SUE_C_SUEC1201_2","NS3 PROTEASE, NS4A PROTEIN","4fuv","PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE","Acinetobacter baumannii",4,"TYR A  41;ILE A  17;LEU A  16;LYS A  13","None;C8E A 308 ( 4.9A);C8E A 308 (-4.8A);None","1.16A","3sueC-4fuvA:undetectable","3sueC-4fuvA:20.66"],["6FBV_D_FI8D1904_0","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","4fuv","PORIN PROTEIN ASSOCIATED WITH IMIPENEM RESISTANCE","Acinetobacter baumannii",4,"GLN A 125;THR A 188;VAL A 187;SER A 119","None","1.03A","6fbvC-4fuvA:undetectable","6fbvC-4fuvA:12.32"]]