SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fvs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 6 TYR A 185
VAL A 144
ILE A 117
LEU A 212
 None
 1.12A 1j96A-4fvsA:
undetectable		 1j96A-4fvsA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A  70
ASN A  81
VAL A 107
ILE A 146
 None
 0.95A 4eyzA-4fvsA:
undetectable		 4eyzA-4fvsA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A  70
ASN A  81
VAL A 107
ILE A 146
 None
 0.96A 4eyzB-4fvsA:
undetectable		 4eyzB-4fvsA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 7 GLU A  67
GLU A  65
TYR A  88
GLU A 119
 None
 1.24A 4mi4A-4fvsA:
undetectable
4mi4C-4fvsA:
undetectable		 4mi4A-4fvsA:
20.09
4mi4C-4fvsA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 7 GLU A  67
GLU A  65
TYR A  88
GLU A 119
 None
 1.08A 4mj8C-4fvsA:
undetectable		 4mj8C-4fvsA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_E_SPME202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		4 / 5 GLU A  67
GLU A  65
TYR A  88
GLU A 119
 None
 0.96A 4r87E-4fvsA:
undetectable		 4r87E-4fvsA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GZ9_A_TXCA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4fvs PUTATIVE LIPOPROTEIN
(Parabacteroides
distasonis) 		5 / 10 TYR A 206
VAL A 183
ALA A 181
ASN A 126
PRO A 127
 None
 1.38A 6gz9A-4fvsA:
undetectable		 6gz9A-4fvsA:
17.88