SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fw1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4fw1 INTEGRASE
(Rous
sarcoma
virus) 		3 / 3 ARG A 201
MET A 155
ARG A 158
 None
 1.23A 3uvvA-4fw1A:
undetectable		 3uvvA-4fw1A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4fw1 INTEGRASE
(Rous
sarcoma
virus) 		4 / 7 ARG A  53
VAL A 241
VAL A 257
GLY A  54
 None
 1.00A 5x80C-4fw1A:
undetectable
5x80D-4fw1A:
undetectable		 5x80C-4fw1A:
21.43
5x80D-4fw1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4fw1 INTEGRASE
(Rous
sarcoma
virus) 		3 / 3 HIS A 198
ASN A 197
LEU A 196
 None
 0.85A 6f7lB-4fw1A:
undetectable		 6f7lB-4fw1A:
17.42