SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3001_1
(SERUM ALBUMIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 11 LEU A 404
ARG A 441
LEU A 419
ARG A 467
ALA A 442
 None
 1.10A 1hk3A-4fwgA:
2.7		 1hk3A-4fwgA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 10 LEU A 588
ALA A 590
LEU A 592
LEU A 684
ALA A 680
 None
 1.31A 1ie4A-4fwgA:
undetectable
1ie4C-4fwgA:
undetectable		 1ie4A-4fwgA:
12.04
1ie4C-4fwgA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 11 LEU A 517
ALA A 545
ALA A 583
VAL A 499
LEU A 600
 None
None
SLA  A 801 ( 4.2A)
None
None
 1.16A 1rlbF-4fwgA:
undetectable		 1rlbF-4fwgA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 MET A 390
PRO A 391
ASP A 431
ALA A 392
ARG A 432
 None
 1.22A 1s14B-4fwgA:
undetectable		 1s14B-4fwgA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 ALA A 680
LEU A 585
VAL A 610
LEU A 553
ILE A 699
 None
 1.12A 1s9pA-4fwgA:
undetectable		 1s9pA-4fwgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 ASN A 253
HIS A 303
VAL A  88
VAL A 349
LEU A 281
 None
 1.24A 1zgfA-4fwgA:
undetectable		 1zgfA-4fwgA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 9 LEU A 404
ARG A 441
PHE A 409
ARG A 467
ALA A 442
 None
 1.11A 2bxeA-4fwgA:
2.5		 2bxeA-4fwgA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		3 / 3 ARG A 383
GLY A  53
PRO A  54
 None
 0.77A 2hreD-4fwgA:
undetectable		 2hreD-4fwgA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 ASN A 253
HIS A 303
VAL A  88
VAL A 349
LEU A 281
 None
 1.16A 2pouA-4fwgA:
undetectable		 2pouA-4fwgA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 8 PRO A 509
SER A 471
VAL A 504
GLY A 512
 None
None
SLA  A 801 (-4.2A)
None
 1.10A 2qd5A-4fwgA:
undetectable		 2qd5A-4fwgA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 GLY A 584
LEU A 502
SER A 582
ALA A 609
ASN A 650
 None
None
SLA  A 801 (-1.3A)
None
None
 1.00A 2vmyA-4fwgA:
undetectable		 2vmyA-4fwgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 11 LEU A 370
PHE A 326
PHE A 380
VAL A  52
LEU A  51
 None
 1.34A 3a9eB-4fwgA:
undetectable		 3a9eB-4fwgA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 6 LEU A 592
ALA A 677
LEU A 681
THR A 676
 None
 1.09A 3cfqA-4fwgA:
undetectable		 3cfqA-4fwgA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 455
GLY A 415
ASP A 421
LEU A 411
LEU A 404
 None
 1.02A 3cjtC-4fwgA:
undetectable		 3cjtC-4fwgA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 10 ILE A 487
VAL A 503
LYS A 625
GLY A 512
LEU A 479
 None
SLA  A 801 (-3.8A)
SLA  A 801 (-2.9A)
None
None
 1.29A 3em0A-4fwgA:
undetectable		 3em0A-4fwgA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 585
GLY A 584
LEU A 588
ALA A 591
LEU A 600
 None
 1.02A 3gwvA-4fwgA:
undetectable		 3gwvA-4fwgA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 ASN A 253
HIS A 303
VAL A  88
VAL A 349
LEU A 281
 None
 1.20A 3hkuA-4fwgA:
undetectable		 3hkuA-4fwgA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 5 SER A 582
ARG A 513
GLY A 512
GLU A 475
 SLA  A 801 (-1.3A)
None
None
None
 1.22A 3k9fA-4fwgA:
undetectable
3k9fB-4fwgA:
undetectable
3k9fC-4fwgA:
undetectable		 3k9fA-4fwgA:
22.80
3k9fB-4fwgA:
22.80
3k9fC-4fwgA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 GLY A 614
ALA A 677
ILE A 645
ILE A 671
MET A   1
 None
 1.05A 3ld6A-4fwgA:
undetectable		 3ld6A-4fwgA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 6 ALA A 329
ILE A 354
VAL A 358
HIS A  48
 None
 1.13A 3nneG-4fwgA:
undetectable		 3nneG-4fwgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.05A 3nt1A-4fwgA:
undetectable		 3nt1A-4fwgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.06A 3nt1B-4fwgA:
undetectable		 3nt1B-4fwgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.01A 3pghC-4fwgA:
undetectable		 3pghC-4fwgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 0.99A 3pghD-4fwgA:
undetectable		 3pghD-4fwgA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.01A 3rr3A-4fwgA:
undetectable		 3rr3A-4fwgA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.01A 3rr3B-4fwgA:
undetectable		 3rr3B-4fwgA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 7 PHE A 278
PHE A 326
ALA A 272
LEU A 310
 None
 1.08A 3t3sC-4fwgA:
undetectable		 3t3sC-4fwgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 8 PHE A  29
LEU A  39
ILE A  43
THR A  69
 None
 0.83A 4em2A-4fwgA:
undetectable		 4em2A-4fwgA:
12.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		8 / 9 VAL A 503
VAL A 504
VAL A 576
ILE A 578
GLY A 580
SER A 582
ALA A 583
LYS A 625
 SLA  A 801 (-3.8A)
SLA  A 801 (-4.2A)
None
SLA  A 801 ( 4.7A)
SLA  A 801 (-3.1A)
SLA  A 801 (-1.3A)
SLA  A 801 ( 4.2A)
SLA  A 801 (-2.9A)
 0.45A 4fwdA-4fwgA:
55.0		 4fwdA-4fwgA:
99.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 7 LEU A 592
ALA A 677
LEU A 681
THR A 676
 None
 1.11A 4iklA-4fwgA:
undetectable
4iklB-4fwgA:
undetectable		 4iklA-4fwgA:
11.30
4iklB-4fwgA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 GLY A 608
GLY A 584
LEU A 502
SER A 501
ILE A 622
 None
 1.11A 4krhA-4fwgA:
2.4		 4krhA-4fwgA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 GLY A 608
GLY A 584
LEU A 502
SER A 501
ILE A 622
 None
 1.08A 4krhB-4fwgA:
2.4		 4krhB-4fwgA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 MET A 557
LEU A 703
LEU A 569
LEU A 553
ALA A 594
 None
 1.40A 4m11A-4fwgA:
undetectable		 4m11A-4fwgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 GLY A 608
GLY A 584
SER A 501
LEU A 617
VAL A 619
 None
 1.04A 4qdjA-4fwgA:
undetectable		 4qdjA-4fwgA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 ALA A 680
MET A 689
ALA A 685
LEU A 600
MET A 557
 None
 1.48A 4zo1X-4fwgA:
undetectable		 4zo1X-4fwgA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 6 LEU A 592
ALA A 677
LEU A 681
THR A 676
 None
 1.05A 5bojA-4fwgA:
undetectable		 5bojA-4fwgA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 5 SER A 582
ARG A 513
GLY A 628
GLU A 475
 SLA  A 801 (-1.3A)
None
None
None
 1.19A 5btiA-4fwgA:
undetectable
5btiB-4fwgA:
undetectable		 5btiA-4fwgA:
23.09
5btiB-4fwgA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 5 SER A 582
ARG A 513
GLY A 628
GLU A 475
 SLA  A 801 (-1.3A)
None
None
None
 1.07A 5btiC-4fwgA:
undetectable
5btiD-4fwgA:
undetectable		 5btiC-4fwgA:
23.09
5btiD-4fwgA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 6 VAL A 632
ALA A 635
GLN A 483
VAL A 482
 None
 1.00A 5i8fA-4fwgA:
undetectable		 5i8fA-4fwgA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.05A 5ikrB-4fwgA:
undetectable		 5ikrB-4fwgA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 12 LEU A 310
VAL A 335
GLY A 333
ALA A 329
LEU A 330
 None
 1.01A 5jvzA-4fwgA:
undetectable		 5jvzA-4fwgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 8 GLN A 357
GLY A  45
GLU A  40
ILE A 382
 None
 1.03A 5vlmD-4fwgA:
undetectable		 5vlmD-4fwgA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 5 VAL A 674
LEU A 585
VAL A 499
LEU A 502
 None
 0.98A 6bqgA-4fwgA:
undetectable		 6bqgA-4fwgA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		4 / 4 ILE A 311
LEU A  39
HIS A  48
ALA A  42
 None
 0.96A 6ck2C-4fwgA:
undetectable
6ck2D-4fwgA:
undetectable		 6ck2C-4fwgA:
4.40
6ck2D-4fwgA:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 10 LEU A 312
VAL A 358
ILE A 354
ALA A 325
LEU A 330
 None
 0.85A 6h1lA-4fwgA:
undetectable		 6h1lA-4fwgA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4fwg TTC1975 PEPTIDASE
(Meiothermus
taiwanensis) 		5 / 11 LEU A 312
VAL A 358
ILE A 354
ALA A 325
LEU A 330
 None
 0.93A 6h1lB-4fwgA:
undetectable		 6h1lB-4fwgA:
22.04