SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fxc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		5 / 12 LEU A   7
GLY A  34
ALA A  33
VAL A   5
ILE A  18
 None
 1.07A 2f8gA-4fxcA:
undetectable		 2f8gA-4fxcA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		5 / 12 LEU A   7
GLY A  34
ALA A  33
VAL A   5
ILE A  18
 None
 1.03A 2hs2B-4fxcA:
undetectable		 2hs2B-4fxcA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		5 / 12 LEU A   7
GLY A  34
ALA A  33
VAL A   5
ILE A  18
 None
 1.09A 3d20A-4fxcA:
undetectable		 3d20A-4fxcA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		5 / 11 LEU A   7
GLY A  34
ALA A  33
VAL A   5
ILE A  18
 None
 1.06A 3el1A-4fxcA:
undetectable		 3el1A-4fxcA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		5 / 10 LEU A   7
GLY A  34
ALA A  33
VAL A   5
ILE A  18
 None
 1.05A 3nu6B-4fxcA:
undetectable		 3nu6B-4fxcA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4fxc FERREDOXIN
(Arthrospira
platensis) 		4 / 6 VAL A   5
LEU A   7
LEU A  35
LEU A  27
 None
 0.87A 6f6sA-4fxcA:
undetectable
6f6sB-4fxcA:
undetectable		 6f6sA-4fxcA:
21.11
6f6sB-4fxcA:
20.79