SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 LEU A 328
THR A 388
ASN A 288
TYR A 279
 None
None
CL  A 503 ( 4.9A)
None
 1.13A 1afsA-4fxqA:
undetectable		 1afsA-4fxqA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 LEU A 328
THR A 388
ASN A 288
TYR A 279
 None
None
CL  A 503 ( 4.9A)
None
 1.13A 1afsB-4fxqA:
undetectable		 1afsB-4fxqA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 7 ARG A 341
SER A 387
SER A 389
GLN A 429
GLU A 431
 CL  A 503 ( 4.1A)
G9L  A 501 (-4.2A)
G9L  A 501 (-3.0A)
G9L  A 501 (-4.3A)
G9L  A 501 (-3.7A)
 0.64A 2c8aA-4fxqA:
25.2		 2c8aA-4fxqA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 341
SER A 387
SER A 389
GLU A 431
 CL  A 503 ( 4.1A)
G9L  A 501 (-4.2A)
G9L  A 501 (-3.0A)
G9L  A 501 (-3.7A)
 0.50A 2c8aB-4fxqA:
24.5		 2c8aB-4fxqA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 ARG A 341
SER A 387
SER A 389
GLU A 431
 CL  A 503 ( 4.1A)
G9L  A 501 (-4.2A)
G9L  A 501 (-3.0A)
G9L  A 501 (-3.7A)
 0.52A 2c8aC-4fxqA:
24.0		 2c8aC-4fxqA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 341
SER A 387
SER A 389
GLU A 431
 CL  A 503 ( 4.1A)
G9L  A 501 (-4.2A)
G9L  A 501 (-3.0A)
G9L  A 501 (-3.7A)
 0.53A 2c8aD-4fxqA:
24.7		 2c8aD-4fxqA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 LEU A 210
PHE A 218
LEU A  31
PRO A  32
VAL A  35
 None
 1.25A 2qd4A-4fxqA:
undetectable		 2qd4A-4fxqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 LEU A 465
ILE A 467
ILE A 411
ILE A 409
PHE A 440
 None
 0.82A 2ygoA-4fxqA:
undetectable		 2ygoA-4fxqA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 10 ILE A 338
ILE A 411
VAL A 415
GLY A 417
LEU A 390
 None
 1.25A 3em0A-4fxqA:
undetectable		 3em0A-4fxqA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 TYR A 355
GLU A 366
LYS A 351
ASN A 374
 None
 1.34A 3k8mA-4fxqA:
undetectable		 3k8mA-4fxqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 3nloA-4fxqA:
undetectable
3nloB-4fxqA:
undetectable		 3nloA-4fxqA:
23.03
3nloB-4fxqA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.49A 3nlyA-4fxqA:
undetectable
3nlyB-4fxqA:
undetectable		 3nlyA-4fxqA:
22.02
3nlyB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 8 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.11A 3rqwC-4fxqA:
undetectable
3rqwD-4fxqA:
undetectable		 3rqwC-4fxqA:
20.65
3rqwD-4fxqA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 8 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.13A 3rqwF-4fxqA:
undetectable
3rqwJ-4fxqA:
undetectable		 3rqwF-4fxqA:
20.65
3rqwJ-4fxqA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.50A 3svpA-4fxqA:
undetectable
3svpB-4fxqA:
undetectable		 3svpA-4fxqA:
22.02
3svpB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 3ufoA-4fxqA:
undetectable
3ufoB-4fxqA:
undetectable		 3ufoA-4fxqA:
22.02
3ufoB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.40A 3ufpA-4fxqA:
undetectable
3ufpB-4fxqA:
undetectable		 3ufpA-4fxqA:
22.02
3ufpB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.50A 3uftA-4fxqA:
undetectable
3uftB-4fxqA:
undetectable		 3uftA-4fxqA:
22.02
3uftB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 5 PHE A 440
GLY A 417
ILE A 409
VAL A 339
 None
 0.74A 3wrkA-4fxqA:
1.0		 3wrkA-4fxqA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 4cdtA-4fxqA:
undetectable
4cdtB-4fxqA:
undetectable		 4cdtA-4fxqA:
22.02
4cdtB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.49A 4ctrA-4fxqA:
undetectable
4ctrB-4fxqA:
undetectable		 4ctrA-4fxqA:
22.02
4ctrB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 4d31A-4fxqA:
undetectable
4d31B-4fxqA:
undetectable		 4d31A-4fxqA:
22.02
4d31B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 8 GLY A  74
LEU A 105
VAL A 108
TYR A 112
 None
 0.50A 4fgzB-4fxqA:
undetectable		 4fgzB-4fxqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.47A 4imwA-4fxqA:
undetectable
4imwB-4fxqA:
undetectable		 4imwA-4fxqA:
22.02
4imwB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.49A 4kchA-4fxqA:
undetectable
4kchB-4fxqA:
undetectable		 4kchA-4fxqA:
22.02
4kchB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.50A 4kciA-4fxqA:
undetectable
4kciB-4fxqA:
undetectable		 4kciA-4fxqA:
22.02
4kciB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.06A 4twdD-4fxqA:
undetectable
4twdE-4fxqA:
undetectable		 4twdD-4fxqA:
21.35
4twdE-4fxqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.09A 4twdF-4fxqA:
undetectable
4twdJ-4fxqA:
undetectable		 4twdF-4fxqA:
21.35
4twdJ-4fxqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.10A 4twdF-4fxqA:
undetectable
4twdG-4fxqA:
undetectable		 4twdF-4fxqA:
21.35
4twdG-4fxqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 GLU A 129
TYR A 220
LEU A 217
PHE A 135
 None
 1.09A 4twdI-4fxqA:
undetectable
4twdJ-4fxqA:
undetectable		 4twdI-4fxqA:
21.35
4twdJ-4fxqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.49A 4uh0A-4fxqA:
undetectable
4uh0B-4fxqA:
undetectable		 4uh0A-4fxqA:
22.02
4uh0B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 4upnA-4fxqA:
undetectable
4upnB-4fxqA:
undetectable		 4upnA-4fxqA:
22.02
4upnB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 LEU A 210
ALA A 138
VAL A 142
ALA A 214
ILE A 139
 None
 1.15A 4x1kD-4fxqA:
undetectable		 4x1kD-4fxqA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 PHE A 198
PHE A 194
ASN A 132
LEU A 224
ARG A 228
 None
 1.44A 4z7fC-4fxqA:
undetectable		 4z7fC-4fxqA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 SER A 331
PHE A 440
LEU A 244
THR A 260
GLY A 257
 None
 1.34A 4zjlA-4fxqA:
undetectable		 4zjlA-4fxqA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.49A 5ad4A-4fxqA:
undetectable
5ad4B-4fxqA:
undetectable		 5ad4A-4fxqA:
22.02
5ad4B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 5ad4A-4fxqA:
undetectable
5ad4B-4fxqA:
undetectable		 5ad4A-4fxqA:
22.02
5ad4B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.49A 5ad5A-4fxqA:
undetectable
5ad5B-4fxqA:
undetectable		 5ad5A-4fxqA:
22.02
5ad5B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.48A 5ad6A-4fxqA:
undetectable
5ad6B-4fxqA:
undetectable		 5ad6A-4fxqA:
22.02
5ad6B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.49A 5ad7A-4fxqA:
undetectable
5ad7B-4fxqA:
undetectable		 5ad7A-4fxqA:
22.02
5ad7B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.48A 5ad8A-4fxqA:
undetectable
5ad8B-4fxqA:
undetectable		 5ad8A-4fxqA:
22.02
5ad8B-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.45A 5adbA-4fxqA:
undetectable
5adbB-4fxqA:
undetectable		 5adbA-4fxqA:
22.02
5adbB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 6 GLU A 266
ALA A 327
LEU A 328
TYR A 419
 None
 0.97A 5igiA-4fxqA:
undetectable		 5igiA-4fxqA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.47A 5unuA-4fxqA:
undetectable
5unuB-4fxqA:
undetectable		 5unuA-4fxqA:
22.02
5unuB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.48A 5unyA-4fxqA:
undetectable
5unyB-4fxqA:
undetectable		 5unyA-4fxqA:
22.02
5unyB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.49A 5uo6A-4fxqA:
undetectable
5uo6B-4fxqA:
undetectable		 5uo6A-4fxqA:
22.31
5uo6B-4fxqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.49A 5vuiA-4fxqA:
undetectable
5vuiB-4fxqA:
undetectable		 5vuiA-4fxqA:
22.02
5vuiB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.48A 5vuiA-4fxqA:
undetectable
5vuiB-4fxqA:
undetectable		 5vuiA-4fxqA:
22.02
5vuiB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.50A 5vujA-4fxqA:
undetectable
5vujB-4fxqA:
undetectable		 5vujA-4fxqA:
22.02
5vujB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.50A 5vuoA-4fxqA:
undetectable
5vuoB-4fxqA:
undetectable		 5vuoA-4fxqA:
22.02
5vuoB-4fxqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 ARG A 160
VAL A 178
PHE A 164
GLU A 189
 None
 1.48A 5vv5A-4fxqA:
undetectable
5vv5B-4fxqA:
undetectable		 5vv5A-4fxqA:
22.31
5vv5B-4fxqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		4 / 7 PHE A 164
GLU A 189
ARG A 160
VAL A 178
 None
 1.48A 6auqA-4fxqA:
undetectable
6auqB-4fxqA:
undetectable		 6auqA-4fxqA:
10.00
6auqB-4fxqA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 THR A 439
THR A 379
ASP A 295
GLY A 437
HIS A 383
 None
 1.32A 6exiA-4fxqA:
undetectable		 6exiA-4fxqA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 THR A 439
THR A 379
ASP A 295
GLY A 437
HIS A 383
 None
 1.29A 6exiD-4fxqA:
undetectable		 6exiD-4fxqA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 4fxq PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX
(Bacillus
cereus) 		5 / 12 ASP A 245
GLN A 127
TRP A 248
ASP A 401
ASP A 393
 None
 1.47A 6fzbB-4fxqA:
0.9		 6fzbB-4fxqA:
7.91