SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fxt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 SER A  49
GLY A  48
ARG A 202
 None
 0.61A 1t9wA-4fxtA:
undetectable		 1t9wA-4fxtA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 11 LEU A 156
ILE A 154
LEU A 173
ARG A 202
GLY A 204
 None
 1.38A 2bxmA-4fxtA:
undetectable		 2bxmA-4fxtA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 ALA A  36
PHE A  52
ALA A  92
PRO A  93
 None
 0.84A 4du2B-4fxtA:
undetectable		 4du2B-4fxtA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 LEU A 223
VAL A 194
PRO A 190
TYR A 200
 None
 0.90A 4lb2A-4fxtA:
undetectable		 4lb2A-4fxtA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		6 / 12 LEU A 171
ILE A 140
PHE A 120
VAL A 152
GLY A 153
ILE A 154
 None
 1.35A 5j2tC-4fxtA:
undetectable		 5j2tC-4fxtA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 4fxt UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 PRO A  93
ARG A  96
GLU A 212
 None
 0.94A 5j6hA-4fxtA:
3.6		 5j6hA-4fxtA:
21.31