SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 GLY A 220
LEU A 154
LEU A 256
LEU A 372
TYR A 379
 None
 1.02A 1fm6D-4fz2A:
undetectable		 1fm6D-4fz2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		4 / 7 VAL A 126
GLY A 128
THR A 137
ILE A 139
 None
 0.61A 1gtnC-4fz2A:
undetectable
1gtnD-4fz2A:
undetectable		 1gtnC-4fz2A:
13.04
1gtnD-4fz2A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		4 / 6 ILE A 382
TRP A 270
LEU A 326
ILE A 355
 None
 0.88A 2q83B-4fz2A:
undetectable		 2q83B-4fz2A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 LEU A  40
GLY A  45
VAL A  72
ASP A  50
LEU A   5
 None
 0.95A 3cjtC-4fz2A:
undetectable		 3cjtC-4fz2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 LEU A  40
GLY A  45
VAL A  72
ASP A  50
LEU A   5
 None
 0.95A 3cjtG-4fz2A:
undetectable		 3cjtG-4fz2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 LEU A  40
GLY A  45
VAL A  72
ASP A  50
LEU A   5
 None
 0.95A 3cjtK-4fz2A:
undetectable		 3cjtK-4fz2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		3 / 3 TYR A 304
ARG A 102
SER A 318
 None
 1.15A 4dr2I-4fz2A:
undetectable
4dr2J-4fz2A:
undetectable		 4dr2I-4fz2A:
16.46
4dr2J-4fz2A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 GLY A 128
VAL A 138
THR A 137
LEU A 171
ASN A 169
 None
 1.24A 4f84A-4fz2A:
undetectable		 4f84A-4fz2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 4fz2 TRNA INTRON
ENDONUCLEASE
(Candidatus
Micrarchaeum
acidiphilum) 		5 / 12 LEU A 256
ILE A 173
ASP A 172
LEU A 179
THR A 176
 None
 1.32A 5tiwB-4fz2A:
undetectable		 5tiwB-4fz2A:
20.00