SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1867_0 (FPRA)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	4 / 4	ALA H 40 ARG H 38 GLN H 43 GLU H 46	None	0.82A	1lqtB-4fzeH: undetectable	1lqtB-4fzeH: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	4 / 4	ALA H 40 ARG H 38 GLN H 43 GLU H 46	None	0.83A	1lquB-4fzeH: undetectable	1lquB-4fzeH: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M2O_B_DHIB24_0 (INSULIN B CHAIN)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	GLY H 50 PHE H 33 PRO H 52 THR H 56	None	1.03A	2m2oB-4fzeH: undetectable	2m2oB-4fzeH: 9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB927_0 (FERROCHELATASE)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	3 / 3	LEU H 138 PRO H 126 ARG H 210	None	0.63A	2qd4B-4fzeH: undetectable	2qd4B-4fzeH: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_B_VIAB901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	4fze	N26_I1 FAB HEAVY CHAIN (Homo sapiens)	5 / 11	TYR H 145 HIS H 200 LEU H 108 ALA H 168 THR H 87	None	1.11A	3jwqB-4fzeH: undetectable 3jwqC-4fzeH: undetectable	3jwqB-4fzeH: 19.77 3jwqC-4fzeH: 19.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_B_ACTB1867_0","FPRA","4fze","N26_I1 FAB HEAVY CHAIN","Homo sapiens",4,"ALA H  40;ARG H  38;GLN H  43;GLU H  46","None","0.82A","1lqtB-4fzeH:undetectable","1lqtB-4fzeH:19.46"],["1LQU_B_ACTB1424_0","FPRA","4fze","N26_I1 FAB HEAVY CHAIN","Homo sapiens",4,"ALA H  40;ARG H  38;GLN H  43;GLU H  46","None","0.83A","1lquB-4fzeH:undetectable","1lquB-4fzeH:19.46"],["2M2O_B_DHIB24_0","INSULIN B CHAIN","4fze","N26_I1 FAB HEAVY CHAIN","Homo sapiens",4,"GLY H  50;PHE H  33;PRO H  52;THR H  56","None","1.03A","2m2oB-4fzeH:undetectable","2m2oB-4fzeH:9.05"],["2QD4_B_CHDB927_0","FERROCHELATASE","4fze","N26_I1 FAB HEAVY CHAIN","Homo sapiens",3,"LEU H 138;PRO H 126;ARG H 210","None","0.63A","2qd4B-4fzeH:undetectable","2qd4B-4fzeH:19.83"],["3JWQ_B_VIAB901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA;CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","4fze","N26_I1 FAB HEAVY CHAIN","Homo sapiens",5,"TYR H 145;HIS H 200;LEU H 108;ALA H 168;THR H  87","None","1.11A","3jwqB-4fzeH:undetectable;3jwqC-4fzeH:undetectable","3jwqB-4fzeH:19.77;3jwqC-4fzeH:19.77"]]