SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 1a4gA-4fzhA:
23.2		 1a4gA-4fzhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.68A 1a4gB-4fzhA:
23.1		 1a4gB-4fzhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 11 THR A 188
THR A 243
LEU A 206
GLY A 273
VAL A 312
 None
 1.20A 1akdA-4fzhA:
undetectable		 1akdA-4fzhA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 TYR A 262
VAL A 296
GLY A 318
GLY A 319
 None
 0.84A 1ekjE-4fzhA:
undetectable
1ekjF-4fzhA:
undetectable		 1ekjE-4fzhA:
17.88
1ekjF-4fzhA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 4 GLY A 246
LEU A 245
GLY A 276
ARG A 274
 None
 1.43A 1j7kA-4fzhA:
undetectable		 1j7kA-4fzhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifA-4fzhA:
undetectable		 1kifA-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifB-4fzhA:
undetectable		 1kifB-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifC-4fzhA:
undetectable		 1kifC-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifD-4fzhA:
undetectable		 1kifD-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifE-4fzhA:
undetectable		 1kifE-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifF-4fzhA:
undetectable		 1kifF-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifG-4fzhA:
undetectable		 1kifG-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.06A 1kifH-4fzhA:
undetectable		 1kifH-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.73A 1nncA-4fzhA:
8.4		 1nncA-4fzhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 SER A 237
SER A 252
VAL A 369
PHE A 364
ALA A 400
 None
 1.47A 1q23D-4fzhA:
undetectable
1q23E-4fzhA:
undetectable		 1q23D-4fzhA:
16.29
1q23E-4fzhA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.07A 1tv8A-4fzhA:
undetectable		 1tv8A-4fzhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.13A 1tv8B-4fzhA:
undetectable		 1tv8B-4fzhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ILE A 565
ALA A 504
PHE A 156
GLN A 157
PRO A 560
 None
 1.44A 1u70A-4fzhA:
undetectable		 1u70A-4fzhA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 299
TYR A 317
PHE A 364
ARG A 498
TYR A 526
 None
 0.92A 1v3eA-4fzhA:
47.1		 1v3eA-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 10 TYR A 299
TYR A 317
GLU A 401
ARG A 416
ARG A 498
 None
 0.78A 1v3eA-4fzhA:
47.1		 1v3eA-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 498
TYR A 526
 None
 0.92A 1v3eA-4fzhA:
47.1		 1v3eA-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 GLU A 258
TYR A 299
TYR A 317
PHE A 364
ARG A 498
TYR A 526
 None
 0.96A 1v3eB-4fzhA:
47.2		 1v3eB-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 10 TYR A 299
TYR A 317
GLU A 401
ARG A 416
ARG A 498
 None
 0.77A 1v3eB-4fzhA:
47.2		 1v3eB-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 10 TYR A 299
TYR A 317
PHE A 364
GLU A 401
ARG A 498
TYR A 526
 None
 0.95A 1v3eB-4fzhA:
47.2		 1v3eB-4fzhA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 470
TYR A 526
ILE A 175
GLY A 402
 None
 1.05A 1ve9A-4fzhA:
undetectable		 1ve9A-4fzhA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.73A 2cmlA-4fzhA:
21.9		 2cmlA-4fzhA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 2cmlB-4fzhA:
22.0		 2cmlB-4fzhA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.70A 2cmlC-4fzhA:
22.1		 2cmlC-4fzhA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.67A 2cmlD-4fzhA:
22.1		 2cmlD-4fzhA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
TYR A 317
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.76A 2f0zA-4fzhA:
27.7		 2f0zA-4fzhA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		7 / 12 ARG A 174
ILE A 175
TYR A 317
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.95A 2f10A-4fzhA:
27.4		 2f10A-4fzhA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.09A 2fb2A-4fzhA:
undetectable		 2fb2A-4fzhA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 471
THR A 527
SER A 544
VAL A 563
 None
 1.04A 2fb2B-4fzhA:
undetectable		 2fb2B-4fzhA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.83A 2htqA-4fzhA:
16.4		 2htqA-4fzhA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 ALA A 525
ALA A 546
SER A 544
GLY A 489
 None
 0.91A 2vh3B-4fzhA:
undetectable		 2vh3B-4fzhA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.13A 2x45A-4fzhA:
undetectable		 2x45A-4fzhA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.14A 2x45B-4fzhA:
undetectable		 2x45B-4fzhA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.12A 2x45C-4fzhA:
undetectable		 2x45C-4fzhA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
ILE A 175
TYR A 317
ARG A 416
ARG A 498
TYR A 526
 None
 0.94A 2ya7A-4fzhA:
10.4		 2ya7A-4fzhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
ILE A 175
TYR A 317
ARG A 416
ARG A 498
TYR A 526
 None
 0.95A 2ya7B-4fzhA:
4.0		 2ya7B-4fzhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
ILE A 175
TYR A 317
ARG A 416
ARG A 498
TYR A 526
 None
 0.94A 2ya7C-4fzhA:
5.3		 2ya7C-4fzhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
ILE A 175
TYR A 317
ARG A 416
ARG A 498
TYR A 526
 None
 0.95A 2ya7D-4fzhA:
13.1		 2ya7D-4fzhA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.70A 3b7eA-4fzhA:
6.7		 3b7eA-4fzhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.69A 3b7eB-4fzhA:
7.7		 3b7eB-4fzhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 324
VAL A 390
ASP A 294
TRP A 295
 None
 1.15A 3bu1A-4fzhA:
undetectable		 3bu1A-4fzhA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ckzA-4fzhA:
22.7		 3ckzA-4fzhA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 132
ILE A 545
LEU A 543
PHE A 532
 None
 1.17A 3ls4L-4fzhA:
undetectable		 3ls4L-4fzhA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.72A 3sanA-4fzhA:
7.7		 3sanA-4fzhA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3sanB-4fzhA:
4.2		 3sanB-4fzhA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 ARG A 605
GLN A 496
PRO A 450
LEU A 499
 None
 1.19A 3tgvB-4fzhA:
undetectable		 3tgvB-4fzhA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 ARG A 605
GLN A 496
PRO A 450
LEU A 499
 None
 1.18A 3tgvD-4fzhA:
undetectable		 3tgvD-4fzhA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ti5A-4fzhA:
8.9		 3ti5A-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ti5B-4fzhA:
9.3		 3ti5B-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ticA-4fzhA:
11.3		 3ticA-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ticB-4fzhA:
22.7		 3ticB-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 3ticC-4fzhA:
11.4		 3ticC-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.70A 3ticD-4fzhA:
22.8		 3ticD-4fzhA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.87A 3u9hA-4fzhA:
undetectable		 3u9hA-4fzhA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.89A 3u9hB-4fzhA:
undetectable		 3u9hB-4fzhA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.73A 4b7nA-4fzhA:
8.6		 4b7nA-4fzhA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.73A 4b7qA-4fzhA:
14.4		 4b7qA-4fzhA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.77A 4b7qB-4fzhA:
9.4		 4b7qB-4fzhA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.69A 4b7qC-4fzhA:
22.4		 4b7qC-4fzhA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.81A 4b7qD-4fzhA:
9.2		 4b7qD-4fzhA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.72A 4cpnA-4fzhA:
22.9		 4cpnA-4fzhA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.66A 4cpnB-4fzhA:
23.0		 4cpnB-4fzhA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.66A 4cpzA-4fzhA:
23.0		 4cpzA-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.68A 4cpzB-4fzhA:
23.1		 4cpzB-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.74A 4cpzC-4fzhA:
4.8		 4cpzC-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 4cpzD-4fzhA:
23.1		 4cpzD-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 4cpzE-4fzhA:
23.2		 4cpzE-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.67A 4cpzF-4fzhA:
5.8		 4cpzF-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 4cpzG-4fzhA:
22.9		 4cpzG-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.71A 4cpzH-4fzhA:
23.2		 4cpzH-4fzhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.91A 4hyfA-4fzhA:
undetectable		 4hyfA-4fzhA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 468
TYR A 470
ALA A 400
SER A 418
 None
 0.87A 4hyfC-4fzhA:
undetectable		 4hyfC-4fzhA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.68A 4i00A-4fzhA:
12.3		 4i00A-4fzhA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 402
THR A 528
TRP A 615
ARG A 416
 None
 1.16A 4m5mA-4fzhA:
undetectable		 4m5mA-4fzhA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 ILE A 227
LEU A 229
ASP A 231
ASP A 230
 None
 1.04A 4mmcA-4fzhA:
undetectable		 4mmcA-4fzhA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.73A 4mwrA-4fzhA:
8.1		 4mwrA-4fzhA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.63A 4wa5A-4fzhA:
4.9		 4wa5A-4fzhA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ASP A 198
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 1.06A 4wa5A-4fzhA:
4.9		 4wa5A-4fzhA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 ASP A 198
TYR A 526
GLU A 547
ILE A 558
 None
 0.94A 4xjeA-4fzhA:
undetectable		 4xjeA-4fzhA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 LEU A 543
ILE A 545
ALA A 546
THR A 490
 None
 0.75A 4zf8A-4fzhA:
undetectable		 4zf8A-4fzhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 ASP A 198
TYR A 526
GLU A 547
ILE A 558
 None
 0.97A 5cfsA-4fzhA:
undetectable		 5cfsA-4fzhA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 ARG A 174
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.70A 5l17A-4fzhA:
6.8		 5l17A-4fzhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 10 VAL A 469
GLU A 401
LEU A 608
ALA A 525
PHE A 556
 None
 1.36A 5mm4B-4fzhA:
undetectable		 5mm4B-4fzhA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 4fzh HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		6 / 12 ARG A 174
ILE A 175
GLU A 401
ARG A 416
ARG A 498
TYR A 526
 None
 0.91A 6ekuA-4fzhA:
24.5		 6ekuA-4fzhA:
21.64