SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 207
PRO A   2
VAL A 156
GLY A 157
 None
 0.99A 1hrkA-4fznA:
undetectable		 1hrkA-4fznA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 207
PRO A   2
VAL A 156
GLY A 157
 None
 1.00A 1hrkB-4fznA:
undetectable		 1hrkB-4fznA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 TYR A 261
PRO A 122
THR A 201
THR A 133
 None
 1.33A 1ymxB-4fznA:
undetectable		 1ymxB-4fznA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TYR A   9
VAL A 126
THR A  11
 None
 0.75A 2ygnA-4fznA:
undetectable		 2ygnA-4fznA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 GLN A 154
LEU A 202
LEU A 149
LEU A 269
 None
 0.96A 3g8iA-4fznA:
undetectable		 3g8iA-4fznA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 TYR A  13
LEU A 149
GLN A  88
TYR A   9
 None
 1.28A 3po7A-4fznA:
undetectable		 3po7A-4fznA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 PRO A 121
SER A 110
ASP A 106
ILE A 107
ILE A 117
 None
 1.46A 4ktvC-4fznA:
undetectable
4ktvD-4fznA:
undetectable		 4ktvC-4fznA:
22.33
4ktvD-4fznA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 TRP A 244
LEU A  80
LEU A 149
ALA A 147
GLY A 141
 None
 1.26A 4rn6A-4fznA:
undetectable		 4rn6A-4fznA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 TYR A 120
ASP A  87
ILE A 103
TYR A   9
 None
 1.26A 5ih0A-4fznA:
undetectable		 5ih0A-4fznA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 ILE A 213
TRP A 221
ARG A 176
VAL A 168
 None
 0.98A 5vlmF-4fznA:
1.6		 5vlmF-4fznA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4fzn BACTERIOCIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PHE A  72
TYR A  54
LEU A  47
ILE A 117
LEU A 249
 None
 1.23A 5y2tA-4fznA:
undetectable		 5y2tA-4fznA:
undetectable