SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		4 / 8 SER A 232
VAL A 229
ARG A 240
ALA A 235
 None
 1.02A 1dmiA-4g0jA:
undetectable
1dmiB-4g0jA:
undetectable		 1dmiA-4g0jA:
20.85
1dmiB-4g0jA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		5 / 12 GLY A 141
VAL A  93
LEU A  91
LEU A   4
LEU A  88
 None
 0.99A 1mx1F-4g0jA:
undetectable		 1mx1F-4g0jA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.83A 1nodB-4g0jA:
undetectable		 1nodB-4g0jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.90A 1qomA-4g0jA:
undetectable		 1qomA-4g0jA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.81A 2nodB-4g0jA:
undetectable		 2nodB-4g0jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.86A 3e7iB-4g0jA:
undetectable		 3e7iB-4g0jA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		5 / 12 ARG A 227
ARG A 240
HIS A 237
HIS A 221
ILE A 179
 None
 1.47A 3njzA-4g0jA:
undetectable		 3njzA-4g0jA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.86A 3nw2A-4g0jA:
undetectable		 3nw2A-4g0jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		3 / 3 ARG A 227
ILE A 265
TRP A 269
 None
 0.81A 3nw2B-4g0jA:
undetectable		 3nw2B-4g0jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		4 / 7 HIS A 174
ILE A 116
VAL A 115
GLN A 175
 None
 1.03A 5kkzC-4g0jA:
undetectable
5kkzE-4g0jA:
undetectable		 5kkzC-4g0jA:
19.31
5kkzE-4g0jA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		4 / 7 ILE A 116
VAL A 115
GLN A 175
HIS A 174
 None
 1.00A 5kkzK-4g0jA:
undetectable
5kkzQ-4g0jA:
undetectable		 5kkzK-4g0jA:
19.87
5kkzQ-4g0jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		4 / 7 HIS A 174
ILE A 116
VAL A 115
GLN A 175
 None
 1.09A 5kkzM-4g0jA:
undetectable
5kkzO-4g0jA:
undetectable		 5kkzM-4g0jA:
19.31
5kkzO-4g0jA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4g0j NON-STRUCTURAL
PROTEIN 2
(Rotavirus
A) 		4 / 5 ASN A 120
GLN A 122
ASP A 123
ARG A 117
 None
 1.14A 5w4zA-4g0jA:
undetectable		 5w4zA-4g0jA:
13.64