SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 10 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 1.06A 2aclC-4g0oA:
undetectable		 2aclC-4g0oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 11 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 1.08A 2aclE-4g0oA:
undetectable		 2aclE-4g0oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 11 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 1.00A 3fc6A-4g0oA:
undetectable		 3fc6A-4g0oA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 12 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 0.98A 3oapA-4g0oA:
undetectable		 3oapA-4g0oA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 12 LEU A 639
ILE A 622
ILE A 663
CYH A 657
ILE A 656
 None
 1.30A 3uj7A-4g0oA:
undetectable		 3uj7A-4g0oA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 12 ILE A 629
ALA A 611
ILE A 653
CYH A 657
LEU A 661
 None
 1.19A 3uvvB-4g0oA:
undetectable		 3uvvB-4g0oA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 12 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 1.01A 3uvvB-4g0oA:
undetectable		 3uvvB-4g0oA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g0o PROTEIN ARGONAUTE 5
(Arabidopsis
thaliana) 		5 / 12 ILE A 629
ALA A 633
ALA A 611
ILE A 653
CYH A 657
 None
 1.03A 6a60D-4g0oA:
undetectable		 6a60D-4g0oA:
17.65