SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 130
LEU A 153
LEU A 216
CYH A 218
 None
 1.05A 2ab2B-4g1hA:
undetectable		 2ab2B-4g1hA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 229
LEU A 137
CYH A 218
THR A 219
 None
 1.35A 2oaxD-4g1hA:
undetectable		 2oaxD-4g1hA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 LEU A 142
PRO A 143
ARG A  65
 None
 0.37A 2qd4B-4g1hA:
undetectable		 2qd4B-4g1hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 LEU A 142
PRO A 143
ARG A  65
 None
 0.66A 2qd5A-4g1hA:
undetectable		 2qd5A-4g1hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ALA A 123
ILE A 182
GLY A 108
SER A 151
VAL A 144
 None
 1.31A 4r20B-4g1hA:
undetectable		 4r20B-4g1hA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ASN A  73
HIS A 136
VAL A 144
LEU A 101
ALA A  98
 None
 1.18A 4yhaF-4g1hA:
undetectable		 4yhaF-4g1hA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ILE A 112
PRO A 113
ILE A 115
 None
 0.45A 5hw8F-4g1hA:
undetectable		 5hw8F-4g1hA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 8 GLN A 106
ASP A 118
GLY A 108
THR A 180
 None
 0.89A 5hwaA-4g1hA:
undetectable		 5hwaA-4g1hA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ILE A 193
ILE A 176
PHE A 177
VAL A 179
GLU A 233
 None
 1.45A 5igzA-4g1hA:
undetectable		 5igzA-4g1hA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 8 ILE A 112
THR A 217
ALA A 155
LEU A 153
 None
 0.69A 5og9A-4g1hA:
undetectable		 5og9A-4g1hA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ASP A 211
THR A 149
VAL A 179
TYR A 188
 None
 1.11A 5ov9A-4g1hA:
undetectable		 5ov9A-4g1hA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 4g1h SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 LEU A 216
ASP A  84
PRO A  85
ARG A 227
 None
 1.19A 6fgdA-4g1hA:
undetectable		 6fgdA-4g1hA:
21.09