SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4g1i PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 ALA A 286
TYR A 285
TYR A 245
PHE A 250
 None
 1.12A 2ajvH-4g1iA:
undetectable
2ajvL-4g1iA:
undetectable		 2ajvH-4g1iA:
22.05
2ajvL-4g1iA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4g1i PROTEIN PRGH
(Salmonella
enterica) 		5 / 10 ARG A 262
TYR A 354
GLY A 301
THR A 298
ALA A 299
 None
None
None
PO4  A 404 (-3.0A)
None
 1.28A 2coiA-4g1iA:
undetectable
2coiB-4g1iA:
undetectable		 2coiA-4g1iA:
22.04
2coiB-4g1iA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4g1i PROTEIN PRGH
(Salmonella
enterica) 		5 / 10 ARG A 262
TYR A 354
GLY A 301
THR A 298
ALA A 299
 None
None
None
PO4  A 404 (-3.0A)
None
 1.30A 2coiA-4g1iA:
undetectable
2coiB-4g1iA:
undetectable		 2coiA-4g1iA:
22.04
2coiB-4g1iA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 4g1i PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 PRO A 256
TYR A 285
SER A 233
ASN A 229
 None
 1.07A 5l1fC-4g1iA:
undetectable		 5l1fC-4g1iA:
12.70