SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 GLY A 131
SER A 132
LEU A 137
ILE A 114
ALA A 105
 None
 1.41A 2a58A-4g1jA:
undetectable
2a58E-4g1jA:
undetectable		 2a58A-4g1jA:
21.93
2a58E-4g1jA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 ILE A 114
ALA A 105
GLY A 131
SER A 132
LEU A 137
 None
 1.41A 2a58C-4g1jA:
undetectable
2a58D-4g1jA:
undetectable		 2a58C-4g1jA:
21.93
2a58D-4g1jA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 236
LEU A 144
CYH A 225
THR A 226
 None
 1.39A 2oaxD-4g1jA:
undetectable		 2oaxD-4g1jA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 LEU A 149
PRO A 150
ARG A  65
 None
 0.42A 2qd4B-4g1jA:
undetectable		 2qd4B-4g1jA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 LEU A 149
PRO A 150
ARG A  65
 None
 0.51A 2qd5A-4g1jA:
undetectable		 2qd5A-4g1jA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 ALA A 158
ILE A 186
ILE A 119
PRO A 120
LEU A 175
 None
 1.04A 3clbA-4g1jA:
undetectable		 3clbA-4g1jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ALA A 158
ILE A 186
ILE A 119
PRO A 120
LEU A 175
 None
 1.07A 3hbbA-4g1jA:
undetectable		 3hbbA-4g1jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ILE A 128
LEU A 160
ILE A 118
PHE A 184
GLY A 239
 None
 1.34A 3sj4X-4g1jA:
undetectable		 3sj4X-4g1jA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 TYR A 212
LEU A 236
ASP A  90
VAL A 141
 None
 1.24A 4nkvA-4g1jA:
undetectable		 4nkvA-4g1jA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ARG A 139
GLN A 113
GLU A 112
 None
 0.84A 4tvtA-4g1jA:
undetectable		 4tvtA-4g1jA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ASN A  73
HIS A 143
VAL A 151
LEU A 108
ALA A 105
 None
 1.23A 4yhaF-4g1jA:
undetectable		 4yhaF-4g1jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 GLY A 181
ASP A 252
GLN A 258
GLY A 239
ILE A 242
 None
 0.85A 5kb6B-4g1jA:
undetectable		 5kb6B-4g1jA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 8 ILE A 119
THR A 224
ALA A 162
LEU A 160
 None
 0.66A 5og9A-4g1jA:
undetectable		 5og9A-4g1jA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 HIS A 143
VAL A 151
LEU A 149
ALA A 158
 None
 1.42A 6d8pB-4g1jA:
undetectable		 6d8pB-4g1jA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 4g1j SORTASE FAMILY
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 LEU A 223
ASP A  90
PRO A  91
ARG A 234
 None
 1.29A 6fgdA-4g1jA:
undetectable		 6fgdA-4g1jA:
19.09