SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		4 / 5 ALA A 253
ALA A 266
LYS A 265
GLU A 262
 None
 1.08A 1e7cA-4g1tA:
2.3		 1e7cA-4g1tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		3 / 3 ARG A 292
ARG A 258
ILE A 339
 None
 0.94A 4b7qA-4g1tA:
undetectable		 4b7qA-4g1tA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		4 / 7 GLU A 354
GLU A 351
TYR A 355
LYS A 359
 None
 0.95A 4fgzA-4g1tA:
undetectable		 4fgzA-4g1tA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		4 / 7 CYH A 289
ILE A 287
LEU A 323
ALA A 326
 None
 0.90A 5hrqE-4g1tA:
undetectable
5hrqF-4g1tA:
undetectable
5hrqJ-4g1tA:
undetectable		 5hrqE-4g1tA:
4.53
5hrqF-4g1tA:
6.40
5hrqJ-4g1tA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		3 / 3 VAL A 336
GLN A 286
CYH A 289
 None
 0.73A 5icxC-4g1tA:
undetectable
5icxF-4g1tA:
undetectable		 5icxC-4g1tA:
17.72
5icxF-4g1tA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		4 / 8 GLU A 173
GLY A 143
LEU A 147
THR A 145
 None
 0.97A 5sxtB-4g1tA:
2.5		 5sxtB-4g1tA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4g1t INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 2
(Homo
sapiens) 		4 / 8 GLU A 173
GLY A 143
LEU A 147
THR A 145
 None
 0.94A 5syjB-4g1tA:
undetectable		 5syjB-4g1tA:
20.03