SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 PHE A 217
TYR A 270
TYR A 271
THR A 272
 None
 1.22A 2q6kA-4g2bA:
undetectable		 2q6kA-4g2bA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 VAL A 257
VAL A 220
ASP A 227
VAL A 229
 None
 1.02A 2qbnA-4g2bA:
undetectable		 2qbnA-4g2bA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.95A 2v2gA-4g2bA:
undetectable
2v2gB-4g2bA:
undetectable		 2v2gA-4g2bA:
21.25
2v2gB-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.98A 2v2gA-4g2bA:
undetectable
2v2gB-4g2bA:
undetectable		 2v2gA-4g2bA:
21.25
2v2gB-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.97A 2v2gC-4g2bA:
undetectable
2v2gD-4g2bA:
undetectable		 2v2gC-4g2bA:
21.25
2v2gD-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 7 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 1.01A 2v2gC-4g2bA:
undetectable
2v2gD-4g2bA:
undetectable		 2v2gC-4g2bA:
21.25
2v2gD-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 8 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.98A 2v32A-4g2bA:
undetectable
2v32B-4g2bA:
undetectable		 2v32A-4g2bA:
21.25
2v32B-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 8 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.98A 2v32A-4g2bA:
undetectable
2v32B-4g2bA:
undetectable		 2v32A-4g2bA:
21.25
2v32B-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 8 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.94A 2v32C-4g2bA:
undetectable
2v32D-4g2bA:
undetectable		 2v32C-4g2bA:
21.25
2v32D-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 8 THR A 183
PRO A 184
VAL A 185
SER A 186
 None
 0.99A 2v32C-4g2bA:
undetectable
2v32D-4g2bA:
undetectable		 2v32C-4g2bA:
21.25
2v32D-4g2bA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		5 / 10 PHE A 194
ALA A 218
PHE A 230
PHE A 188
LEU A 161
 None
 1.40A 3a3yA-4g2bA:
undetectable		 3a3yA-4g2bA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 6 VAL A 219
VAL A 220
PHE A 188
ARG A 200
 None
 1.16A 3bjwF-4g2bA:
undetectable		 3bjwF-4g2bA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 5 TYR A 199
GLY A 221
ASP A 227
VAL A 302
 None
 0.89A 4nkvD-4g2bA:
undetectable		 4nkvD-4g2bA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		3 / 3 PRO A 184
VAL A 232
HIS A 235
 None
 0.77A 4pevC-4g2bA:
undetectable		 4pevC-4g2bA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		5 / 12 ALA A 234
SER A 233
PHE A 237
THR A 264
ARG A 261
 None
 1.27A 5hnzB-4g2bA:
undetectable		 5hnzB-4g2bA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4g2b SECRETED EFFECTOR
PROTEIN SSEI
(Salmonella
enterica) 		4 / 6 LYS A 267
LEU A 268
PHE A 203
PHE A 311
 None
 1.01A 5w97C-4g2bA:
undetectable
5w97J-4g2bA:
undetectable		 5w97C-4g2bA:
19.71
5w97J-4g2bA:
13.83