SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g2u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		3 / 3 ALA A 165
VAL A 145
TRP A  59
 None
 0.88A 1nt6A-4g2uA:
undetectable		 1nt6A-4g2uA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		3 / 3 ALA A 165
VAL A 145
TRP A  59
 None
 0.88A 1nt6B-4g2uA:
undetectable		 1nt6B-4g2uA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RFF_A_SPMA700_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1
TOPOISOMERASE
I-DERIVED PEPTIDE)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 4 ASN A 142
TRP A 140
VAL A 177
TYR A  55
 None
 1.43A 1rffA-4g2uA:
0.0
1rffC-4g2uA:
undetectable		 1rffA-4g2uA:
17.08
1rffC-4g2uA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 6 SER A 135
ILE A 131
ALA A 124
ALA A  51
 None
 0.90A 1w0gA-4g2uA:
undetectable		 1w0gA-4g2uA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 5 MET A 160
LEU A  93
PRO A 107
SER A 109
 None
 1.23A 4kmmB-4g2uA:
undetectable		 4kmmB-4g2uA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 7 PHE A  21
HIS A  22
ILE A 137
TYR A 166
 None
 0.80A 4o7gA-4g2uA:
undetectable
4o7gB-4g2uA:
undetectable		 4o7gA-4g2uA:
19.69
4o7gB-4g2uA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 5 GLY A  31
ALA A  30
GLY A  49
PRO A  50
 None
 0.91A 4u9uA-4g2uA:
undetectable		 4u9uA-4g2uA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4g2u ANCYLOSTOMA-SECRETED
PROTEIN-LIKE PROTEIN
(Ostertagia
ostertagi) 		4 / 5 GLY A  31
ALA A  30
GLY A  49
PRO A  50
 None
 0.90A 4u9uB-4g2uA:
undetectable		 4u9uB-4g2uA:
21.25