SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g43'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L2I_B_CCSB417_0 (ESTROGEN RECEPTOR)	4g43	MHC CLASS I ALPHA CHAIN 2 (Gallus gallus)	4 / 6	PRO A 206 PHE A 204 GLU A 258 VAL A 210	None	1.44A	1l2iB-4g43A: undetectable	1l2iB-4g43A: 18.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3P73_A_ACTA275_0 (MHC RFP-Y CLASS I ALPHA CHAIN)	4g43	MHC CLASS I ALPHA CHAIN 2 (Gallus gallus)	3 / 3	ILE A 107 VAL A 162 ARG A 166	None	0.71A	3p73A-4g43A: 30.4	3p73A-4g43A: 62.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DBY_A_ACTA610_0 (SERUM ALBUMIN)	4g43	MHC CLASS I ALPHA CHAIN 2 (Gallus gallus)	3 / 3	TYR A 253 LYS A 252 LYS A 215	None	1.21A	5dbyA-4g43A: undetectable	5dbyA-4g43A: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_A_ACTA609_0 (NADH DEHYDROGENASE, PUTATIVE)	4g43	MHC CLASS I ALPHA CHAIN 2 (Gallus gallus)	3 / 3	VAL A 186 SER A 269 TRP A 270	None	1.03A	5jwaA-4g43A: undetectable	5jwaA-4g43A: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A4I_A_TRPA403_0 (TRYPTOPHAN 2,3-DIOXYGENASE)	4g43	MHC CLASS I ALPHA CHAIN 2 (Gallus gallus)	4 / 8	TRP A 59 THR A 54 ILE A 50 PRO A 45	None	1.07A	6a4iA-4g43A: undetectable	6a4iA-4g43A: 23.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1L2I_B_CCSB417_0","ESTROGEN RECEPTOR","4g43","MHC CLASS I ALPHA CHAIN 2","Gallus gallus",4,"PRO A 206;PHE A 204;GLU A 258;VAL A 210","None","1.44A","1l2iB-4g43A:undetectable","1l2iB-4g43A:18.21"],["3P73_A_ACTA275_0","MHC RFP-Y CLASS I ALPHA CHAIN","4g43","MHC CLASS I ALPHA CHAIN 2","Gallus gallus",3,"ILE A 107;VAL A 162;ARG A 166","None","0.71A","3p73A-4g43A:30.4","3p73A-4g43A:62.18"],["5DBY_A_ACTA610_0","SERUM ALBUMIN","4g43","MHC CLASS I ALPHA CHAIN 2","Gallus gallus",3,"TYR A 253;LYS A 252;LYS A 215","None","1.21A","5dbyA-4g43A:undetectable","5dbyA-4g43A:17.47"],["5JWA_A_ACTA609_0","NADH DEHYDROGENASE, PUTATIVE","4g43","MHC CLASS I ALPHA CHAIN 2","Gallus gallus",3,"VAL A 186;SER A 269;TRP A 270","None","1.03A","5jwaA-4g43A:undetectable","5jwaA-4g43A:18.47"],["6A4I_A_TRPA403_0","TRYPTOPHAN 2,3-DIOXYGENASE","4g43","MHC CLASS I ALPHA CHAIN 2","Gallus gallus",4,"TRP A  59;THR A  54;ILE A  50;PRO A  45","None","1.07A","6a4iA-4g43A:undetectable","6a4iA-4g43A:23.12"]]