SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g4w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R75_A_BEZA701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	4g4w	PEPTIDOGLYCAN-ASSOCI ATED LIPOPROTEIN (Acinetobacter baumannii)	5 / 12	GLU A 161 SER A 157 GLY A 117 THR A 116 HIS A 118	None	1.46A	3r75A-4g4wA: undetectable	3r75A-4g4wA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R76_A_BEZA701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	4g4w	PEPTIDOGLYCAN-ASSOCI ATED LIPOPROTEIN (Acinetobacter baumannii)	5 / 11	GLU A 161 SER A 157 GLY A 117 THR A 116 HIS A 118	None	1.45A	3r76A-4g4wA: undetectable	3r76A-4g4wA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SGL_A_SAMA692_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	4g4w	PEPTIDOGLYCAN-ASSOCI ATED LIPOPROTEIN (Acinetobacter baumannii)	5 / 12	GLU A 133 GLY A 132 GLY A 117 THR A 116 ASP A 86	None	1.04A	3sglA-4g4wA: undetectable	3sglA-4g4wA: 10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUN_A_Z80A201_1 (BETA-LACTOGLOBULIN)	4g4w	PEPTIDOGLYCAN-ASSOCI ATED LIPOPROTEIN (Acinetobacter baumannii)	5 / 9	ALA A 136 VAL A 139 LEU A 98 ASN A 182 ALA A 155	None	0.73A	5nunA-4g4wA: undetectable	5nunA-4g4wA: 23.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3R75_A_BEZA701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","4g4w","PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN","Acinetobacter baumannii",5,"GLU A 161;SER A 157;GLY A 117;THR A 116;HIS A 118","None","1.46A","3r75A-4g4wA:undetectable","3r75A-4g4wA:12.61"],["3R76_A_BEZA701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","4g4w","PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN","Acinetobacter baumannii",5,"GLU A 161;SER A 157;GLY A 117;THR A 116;HIS A 118","None","1.45A","3r76A-4g4wA:undetectable","3r76A-4g4wA:12.61"],["3SGL_A_SAMA692_0","TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC","4g4w","PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN","Acinetobacter baumannii",5,"GLU A 133;GLY A 132;GLY A 117;THR A 116;ASP A  86","None","1.04A","3sglA-4g4wA:undetectable","3sglA-4g4wA:10.15"],["5NUN_A_Z80A201_1","BETA-LACTOGLOBULIN","4g4w","PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN","Acinetobacter baumannii",5,"ALA A 136;VAL A 139;LEU A  98;ASN A 182;ALA A 155","None","0.73A","5nunA-4g4wA:undetectable","5nunA-4g4wA:23.42"]]