SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOJ_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	4g6a	AP33 LIGHT CHAIN (Homo sapiens)	4 / 5	LEU D 179 GLY D 128 PRO D 120 VAL D 132	None	0.79A	2aojA-4g6aD: undetectable	2aojA-4g6aD: 16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K9W_A_ACTA170_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	4g6a	AP33 LIGHT CHAIN (Homo sapiens)	3 / 3	SER D 127 GLY D 128 THR D 129	None	0.19A	3k9wA-4g6aD: undetectable	3k9wA-4g6aD: 25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4E_D_EDPD402_1 (PROTON-GATED ION CHANNEL)	4g6a	AP33 LIGHT CHAIN (Homo sapiens)	4 / 8	THR D 74 SER D 63 THR D 72 SER D 65	None	1.00A	5l4eA-4g6aD: undetectable 5l4eB-4g6aD: undetectable 5l4eC-4g6aD: undetectable 5l4eD-4g6aD: undetectable 5l4eE-4g6aD: undetectable	5l4eA-4g6aD: 20.25 5l4eB-4g6aD: 20.25 5l4eC-4g6aD: 20.25 5l4eD-4g6aD: 20.25 5l4eE-4g6aD: 20.25