SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 PHE A 132
ILE A 105
LEU A  36
LEU A  69
ILE A 134
 None
 1.33A 1kqwA-4g79A:
undetectable		 1kqwA-4g79A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 LEU A  98
LEU A  36
ILE A  55
ILE A 108
PHE A 118
 None
 1.10A 2h42C-4g79A:
undetectable		 2h42C-4g79A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 10 ILE A  55
PHE A  65
ILE A 105
THR A  32
LEU A 109
 None
None
None
PG4  A 205 (-4.6A)
None
 1.02A 3eqmA-4g79A:
undetectable		 3eqmA-4g79A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 ILE A  95
ILE A  38
LEU A  98
LEU A 120
ILE A 105
 None
 1.00A 3uvvA-4g79A:
undetectable		 3uvvA-4g79A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 VAL A  93
LEU A  99
PHE A 132
ILE A  38
LEU A  36
 None
 1.07A 3w67C-4g79A:
undetectable		 3w67C-4g79A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 11 ILE A  55
PHE A  65
ILE A 105
THR A  32
LEU A 109
 None
None
None
PG4  A 205 (-4.6A)
None
 1.07A 5jkwA-4g79A:
undetectable		 5jkwA-4g79A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 10 ILE A  55
PHE A  65
ILE A 105
THR A  32
LEU A 109
 None
None
None
PG4  A 205 (-4.6A)
None
 1.03A 5jl7A-4g79A:
undetectable		 5jl7A-4g79A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 4g79 SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 PHE A  53
ILE A  38
TYR A  74
LEU A  36
LEU A 120
 None
 1.27A 5zwrB-4g79A:
undetectable		 5zwrB-4g79A:
16.80