SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 7 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.24A 1am6A-4g7aA:
29.9		 1am6A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 7 HIS A  91
HIS A 108
HIS A  89
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
 1.07A 1am6A-4g7aA:
29.9		 1am6A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.27A 1azmA-4g7aA:
28.5		 1azmA-4g7aA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.24A 1bzmA-4g7aA:
28.5		 1bzmA-4g7aA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.28A 1cilA-4g7aA:
30.0		 1cilA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 HIS A  64
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.27A 1cilA-4g7aA:
30.0		 1cilA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.42A 1cilA-4g7aA:
30.0		 1cilA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.29A 1dmyA-4g7aA:
26.5		 1dmyA-4g7aA:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.19A 1dmyB-4g7aA:
26.5		 1dmyB-4g7aA:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 1dmyB-4g7aA:
26.5		 1dmyB-4g7aA:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 1dmyB-4g7aA:
26.5		 1dmyB-4g7aA:
31.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 8 PHE A  88
ILE A 137
LEU A 159
LEU A 201
 None
 0.77A 1eupA-4g7aA:
undetectable		 1eupA-4g7aA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.89A 1jd0A-4g7aA:
30.3		 1jd0A-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.42A 1jd0A-4g7aA:
30.3		 1jd0A-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.87A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.09A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.50A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.39A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.99A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.41A 1jd0B-4g7aA:
29.9		 1jd0B-4g7aA:
27.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 ASN A  62
HIS A  91
LEU A 173
THR A 174
PRO A 177
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.02A 1oq5A-4g7aA:
30.1		 1oq5A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
PRO A 177
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 0.38A 1oq5A-4g7aA:
30.1		 1oq5A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
VAL A 120
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.03A 1oq5A-4g7aA:
30.1		 1oq5A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.38A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.04A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A 108
VAL A 121
LEU A  76
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
None
None
None
 1.24A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
HIS A  89
THR A 175
THR A 174
TRP A   3
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.44A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.41A 1rj6A-4g7aA:
30.3		 1rj6A-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 1rj6B-4g7aA:
30.2		 1rj6B-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.38A 1rj6B-4g7aA:
30.2		 1rj6B-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.04A 1rj6B-4g7aA:
30.2		 1rj6B-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.42A 1rj6B-4g7aA:
30.2		 1rj6B-4g7aA:
30.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 7 ARG A 219
ILE A 221
LEU A  44
GLY A 224
 None
 0.84A 1rtsB-4g7aA:
undetectable		 1rtsB-4g7aA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 10 GLN A  87
HIS A  89
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.35A 1ydaA-4g7aA:
29.5		 1ydaA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.13A 1ydbA-4g7aA:
29.8		 1ydbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.26A 1ydbA-4g7aA:
29.8		 1ydbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.16A 1ydbA-4g7aA:
29.8		 1ydbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.43A 1ydbA-4g7aA:
29.8		 1ydbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.15A 1yddA-4g7aA:
29.9		 1yddA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
THR A 174
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.28A 1yddA-4g7aA:
29.9		 1yddA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
HIS A  89
VAL A 110
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.41A 1yddA-4g7aA:
29.9		 1yddA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.12A 1z9yA-4g7aA:
29.9		 1z9yA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.27A 1z9yA-4g7aA:
29.9		 1z9yA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.36A 1z9yA-4g7aA:
29.9		 1z9yA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 ASN A  62
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.06A 1zgfA-4g7aA:
30.0		 1zgfA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.33A 1zgfA-4g7aA:
30.0		 1zgfA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.32A 1zgfA-4g7aA:
30.0		 1zgfA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.49A 1zgfA-4g7aA:
30.0		 1zgfA-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.93A 1zsbA-4g7aA:
30.0		 1zsbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.21A 1zsbA-4g7aA:
30.0		 1zsbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.48A 1zsbA-4g7aA:
30.0		 1zsbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 1zsbA-4g7aA:
30.0		 1zsbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.41A 1zsbA-4g7aA:
30.0		 1zsbA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.23A 2aw1A-4g7aA:
29.9		 2aw1A-4g7aA:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 TRP A   3
GLN A  87
THR A 175
PRO A 177
 None
AZM  A 302 (-4.4A)
AZM  A 302 (-3.4A)
None
 0.52A 2ez7A-4g7aA:
29.5		 2ez7A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.29A 2gehA-4g7aA:
29.7		 2gehA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 8 HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.91A 2gehA-4g7aA:
29.7		 2gehA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 GLN A  67
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.91A 2h4nA-4g7aA:
30.0		 2h4nA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 9 GLN A  87
HIS A  91
HIS A 108
VAL A 110
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.48A 2h4nA-4g7aA:
30.0		 2h4nA-4g7aA:
33.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 ASN A  62
HIS A  64
GLN A  87
THR A 175
 None
None
AZM  A 302 (-4.4A)
AZM  A 302 (-3.4A)
 0.41A 2hkkA-4g7aA:
29.8		 2hkkA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.35A 2it4A-4g7aA:
28.6		 2it4A-4g7aA:
31.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 LEU A 134
ASN A 209
GLN A  87
ILE A  68
 None
None
AZM  A 302 (-4.4A)
None
 1.22A 2jn3A-4g7aA:
1.2		 2jn3A-4g7aA:
19.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 ASN A  62
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.90A 2pouA-4g7aA:
29.8		 2pouA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 2pouA-4g7aA:
29.8		 2pouA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.11A 2pouA-4g7aA:
29.8		 2pouA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.99A 2pouA-4g7aA:
29.8		 2pouA-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 ILE A  66
THR A  65
LEU A 138
VAL A  59
GLU A 133
ILE A 193
 None
 1.43A 2vn0A-4g7aA:
undetectable		 2vn0A-4g7aA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		3 / 3 TRP A   3
VAL A 120
ARG A 183
 None
AZM  A 302 ( 4.8A)
None
 0.78A 3b0wA-4g7aA:
undetectable		 3b0wA-4g7aA:
21.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.36A 3bl1A-4g7aA:
29.7		 3bl1A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.12A 3bl1A-4g7aA:
29.7		 3bl1A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.08A 3bl1A-4g7aA:
29.7		 3bl1A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.99A 3bl1A-4g7aA:
29.7		 3bl1A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.28A 3cajA-4g7aA:
29.9		 3cajA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  89
HIS A 108
LEU A 173
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 1.49A 3cajA-4g7aA:
29.9		 3cajA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
None
None
 1.29A 3cajA-4g7aA:
29.9		 3cajA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.98A 3cajA-4g7aA:
29.9		 3cajA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
 0.90A 3czvA-4g7aA:
29.4
3czvB-4g7aA:
29.5		 3czvA-4g7aA:
32.28
3czvB-4g7aA:
32.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.50A 3czvA-4g7aA:
29.4
3czvB-4g7aA:
29.5		 3czvA-4g7aA:
32.28
3czvB-4g7aA:
32.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
 0.98A 3czvB-4g7aA:
29.5		 3czvB-4g7aA:
32.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.45A 3czvB-4g7aA:
29.5		 3czvB-4g7aA:
32.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.10A 3dazA-4g7aA:
30.1		 3dazA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.27A 3dazA-4g7aA:
30.1		 3dazA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.10A 3dazA-4g7aA:
30.1		 3dazA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.42A 3dazA-4g7aA:
30.1		 3dazA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.93A 3dc3A-4g7aA:
30.1		 3dc3A-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.21A 3dc3A-4g7aA:
30.1		 3dc3A-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.30A 3dc3A-4g7aA:
30.1		 3dc3A-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.96A 3dcsA-4g7aA:
30.0		 3dcsA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.35A 3dcsA-4g7aA:
30.0		 3dcsA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A 108
HIS A  91
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.48A 3dcsA-4g7aA:
30.0		 3dcsA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 3dcsA-4g7aA:
30.0		 3dcsA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.26A 3dcwA-4g7aA:
30.1		 3dcwA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
None
None
 1.30A 3dcwA-4g7aA:
30.1		 3dcwA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.43A 3dcwA-4g7aA:
30.1		 3dcwA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.93A 3dcwA-4g7aA:
30.1		 3dcwA-4g7aA:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.25A 3dd0A-4g7aA:
29.9		 3dd0A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.09A 3dd0A-4g7aA:
29.9		 3dd0A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.43A 3dd0A-4g7aA:
29.9		 3dd0A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 10 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 1.46A 3dd0A-4g7aA:
29.9		 3dd0A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.93A 3dd0A-4g7aA:
29.9		 3dd0A-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 ARG A 219
ILE A  98
GLY A 122
ILE A  32
ILE A  34
 None
 0.95A 3ebzA-4g7aA:
undetectable		 3ebzA-4g7aA:
21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.45A 3f4xA-4g7aA:
29.5		 3f4xA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 ASN A  62
HIS A  91
LEU A 173
THR A 174
THR A 175
PRO A 177
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.02A 3f4xA-4g7aA:
29.5		 3f4xA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 ASN A  62
HIS A  91
VAL A 110
LEU A 173
THR A 175
PRO A 177
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.97A 3f4xA-4g7aA:
29.5		 3f4xA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.05A 3f4xA-4g7aA:
29.5		 3f4xA-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		12 / 12 ASN A  62
HIS A  64
GLN A  87
HIS A  89
HIS A  91
VAL A 110
ILE A 118
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
None
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.53A 3fw3A-4g7aA:
28.3		 3fw3A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
ILE A 118
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
None
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 3fw3A-4g7aA:
28.3		 3fw3A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  64
GLN A  67
HIS A  89
HIS A  91
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.97A 3fw3A-4g7aA:
28.3		 3fw3A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  64
HIS A  91
ILE A 118
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.31A 3fw3A-4g7aA:
28.3		 3fw3A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		12 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
ILE A 118
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
None
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.40A 3fw3B-4g7aA:
28.2		 3fw3B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
ILE A 118
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
None
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.37A 3fw3B-4g7aA:
28.2		 3fw3B-4g7aA:
29.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 ASN A  62
GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.37A 3hkuA-4g7aA:
29.8		 3hkuA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.30A 3hkuA-4g7aA:
29.8		 3hkuA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.17A 3hkuA-4g7aA:
29.8		 3hkuA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.47A 3hkuA-4g7aA:
29.8		 3hkuA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		3 / 3 GLU A  95
HIS A 108
THR A 174
 AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
 0.08A 3hkuA-4g7aA:
29.8		 3hkuA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.27A 3hs4A-4g7aA:
30.1		 3hs4A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.25A 3hs4A-4g7aA:
30.1		 3hs4A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.49A 3hs4A-4g7aA:
30.1		 3hs4A-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.19A 3iaiA-4g7aA:
29.8		 3iaiA-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.21A 3iaiA-4g7aA:
29.8		 3iaiA-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.94A 3iaiA-4g7aA:
29.8		 3iaiA-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.20A 3iaiB-4g7aA:
29.9		 3iaiB-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.21A 3iaiB-4g7aA:
29.9		 3iaiB-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.93A 3iaiB-4g7aA:
29.9		 3iaiB-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.20A 3iaiC-4g7aA:
29.9		 3iaiC-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.19A 3iaiC-4g7aA:
29.9		 3iaiC-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.93A 3iaiC-4g7aA:
29.9		 3iaiC-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.92A 3iaiD-4g7aA:
29.8		 3iaiD-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.19A 3iaiD-4g7aA:
29.8		 3iaiD-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.19A 3iaiD-4g7aA:
29.8		 3iaiD-4g7aA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.91A 3iaiD-4g7aA:
29.8		 3iaiD-4g7aA:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.43A 3kwaA-4g7aA:
29.4		 3kwaA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 1.38A 3kwaA-4g7aA:
29.4		 3kwaA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.99A 3kwaA-4g7aA:
29.4		 3kwaA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.50A 3lxeA-4g7aA:
28.9		 3lxeA-4g7aA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.49A 3lxeB-4g7aA:
28.9		 3lxeB-4g7aA:
31.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 TYR A 166
LEU A 119
VAL A 120
GLN A  87
HIS A  89
 None
None
AZM  A 302 ( 4.8A)
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
 1.30A 3m7rA-4g7aA:
undetectable		 3m7rA-4g7aA:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.25A 3mdzA-4g7aA:
29.6		 3mdzA-4g7aA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.96A 3mdzA-4g7aA:
29.6		 3mdzA-4g7aA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 1.48A 3mdzA-4g7aA:
29.6		 3mdzA-4g7aA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.22A 3ml5A-4g7aA:
29.9		 3ml5A-4g7aA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.48A 3ml5A-4g7aA:
29.9		 3ml5A-4g7aA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.94A 3ml5A-4g7aA:
29.9		 3ml5A-4g7aA:
36.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 ILE A 137
ALA A 141
LEU A 150
ILE A 107
LEU A 201
 None
 0.94A 3oapA-4g7aA:
undetectable		 3oapA-4g7aA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 ARG A 219
ILE A  98
GLY A 122
ILE A  32
ILE A  34
 None
 1.11A 3s53B-4g7aA:
undetectable		 3s53B-4g7aA:
15.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.27A 3v2jA-4g7aA:
30.1		 3v2jA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.25A 3v2jA-4g7aA:
30.1		 3v2jA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.48A 3v2jA-4g7aA:
30.1		 3v2jA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.25A 3v2mA-4g7aA:
30.0		 3v2mA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.48A 3v2mA-4g7aA:
30.0		 3v2mA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.93A 3v2mA-4g7aA:
30.0		 3v2mA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.37A 3v2mA-4g7aA:
30.0		 3v2mA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 8 GLN A  87
HIS A  89
HIS A  91
HIS A 108
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.38A 3w6hA-4g7aA:
28.7		 3w6hA-4g7aA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
LEU A 173
THR A 174
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.39A 3w6hB-4g7aA:
28.7		 3w6hB-4g7aA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.95A 3zncA-4g7aA:
27.8		 3zncA-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.45A 3zncA-4g7aA:
27.8		 3zncA-4g7aA:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.06A 3zncA-4g7aA:
27.8		 3zncA-4g7aA:
30.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 7 LEU A 173
GLU A 106
HIS A 108
HIS A  89
 AZM  A 302 (-3.8A)
None
ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
 1.24A 4aq7A-4g7aA:
undetectable		 4aq7A-4g7aA:
15.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.25A 4coqA-4g7aA:
34.9		 4coqA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.16A 4coqA-4g7aA:
34.9		 4coqA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.45A 4coqA-4g7aA:
34.9		 4coqA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.96A 4coqA-4g7aA:
34.9		 4coqA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.14A 4coqB-4g7aA:
34.9		 4coqB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.34A 4coqB-4g7aA:
34.9		 4coqB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.98A 4coqB-4g7aA:
34.9		 4coqB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 4coqB-4g7aA:
34.9		 4coqB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 10 GLN A  87
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
VAL A 182
TRP A 184
 AZM  A 302 (-4.4A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.50A 4e3hA-4g7aA:
29.8		 4e3hA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 VAL A 120
LEU A 173
THR A 174
THR A 175
VAL A 182
 AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.06A 4e3hA-4g7aA:
29.8		 4e3hA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.98A 4g0cA-4g7aA:
30.0		 4g0cA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.29A 4g0cA-4g7aA:
30.0		 4g0cA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.22A 4g0cA-4g7aA:
30.0		 4g0cA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.12A 4g0cA-4g7aA:
30.0		 4g0cA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.27A 4k0sA-4g7aA:
30.1		 4k0sA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.49A 4k0sA-4g7aA:
30.1		 4k0sA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.96A 4k0sA-4g7aA:
30.1		 4k0sA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.37A 4k0zA-4g7aA:
30.0		 4k0zA-4g7aA:
34.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.09A 4k0zA-4g7aA:
30.0		 4k0zA-4g7aA:
34.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.34A 4k0zA-4g7aA:
30.0		 4k0zA-4g7aA:
34.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.49A 4k0zA-4g7aA:
30.0		 4k0zA-4g7aA:
34.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.24A 4k13A-4g7aA:
30.0		 4k13A-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.47A 4k13A-4g7aA:
30.0		 4k13A-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.01A 4lu3A-4g7aA:
29.9		 4lu3A-4g7aA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.25A 4lu3A-4g7aA:
29.9		 4lu3A-4g7aA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.40A 4m2rA-4g7aA:
30.0		 4m2rA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.29A 4m2rA-4g7aA:
30.0		 4m2rA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 1.38A 4m2rA-4g7aA:
30.0		 4m2rA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.95A 4m2rA-4g7aA:
30.0		 4m2rA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  64
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.22A 4m2uA-4g7aA:
30.1		 4m2uA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 TRP A   3
GLN A  67
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.16A 4m2uA-4g7aA:
30.1		 4m2uA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 TRP A   3
HIS A  64
GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.34A 4m2uA-4g7aA:
30.1		 4m2uA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 TRP A   3
HIS A  64
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
 None
None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.28A 4m2uA-4g7aA:
30.1		 4m2uA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 TRP A  14
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 175
TRP A 184
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.44A 4m2uA-4g7aA:
30.1		 4m2uA-4g7aA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.25A 4m2vA-4g7aA:
30.1		 4m2vA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
GLY A 116
LEU A 173
THR A 174
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
None
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.21A 4m2vA-4g7aA:
30.1		 4m2vA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.24A 4m2vA-4g7aA:
30.1		 4m2vA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.25A 4m2wA-4g7aA:
30.1		 4m2wA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.22A 4m2wA-4g7aA:
30.1		 4m2wA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.39A 4m2wA-4g7aA:
30.1		 4m2wA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.48A 4m2wA-4g7aA:
30.1		 4m2wA-4g7aA:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 8 GLN A  67
HIS A  89
HIS A  91
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.14A 4n16A-4g7aA:
30.0		 4n16A-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 8 GLN A  87
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.28A 4n16A-4g7aA:
30.0		 4n16A-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 ILE A 137
ALA A 141
LEU A 150
ILE A 107
LEU A 201
 None
 0.89A 4nqaH-4g7aA:
undetectable		 4nqaH-4g7aA:
19.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.31A 4pxxA-4g7aA:
30.1		 4pxxA-4g7aA:
34.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
VAL A 110
VAL A 120
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.4A)
None
 0.31A 4twlA-4g7aA:
30.8		 4twlA-4g7aA:
34.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
VAL A 110
VAL A 120
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.4A)
None
 0.29A 4twlB-4g7aA:
31.2		 4twlB-4g7aA:
34.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.06A 4uovA-4g7aA:
34.7		 4uovA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.25A 4uovA-4g7aA:
34.7		 4uovA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.19A 4uovA-4g7aA:
34.7		 4uovA-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.96A 4uovB-4g7aA:
34.8		 4uovB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.22A 4uovB-4g7aA:
34.8		 4uovB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.50A 4uovB-4g7aA:
34.8		 4uovB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.13A 4uovB-4g7aA:
34.8		 4uovB-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.92A 4uovC-4g7aA:
34.6		 4uovC-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.06A 4uovC-4g7aA:
34.6		 4uovC-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.50A 4uovC-4g7aA:
34.6		 4uovC-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.17A 4uovC-4g7aA:
34.6		 4uovC-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.91A 4uovD-4g7aA:
34.7		 4uovD-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.05A 4uovD-4g7aA:
34.7		 4uovD-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.17A 4uovD-4g7aA:
34.7		 4uovD-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.05A 4uovE-4g7aA:
34.7		 4uovE-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.24A 4uovE-4g7aA:
34.7		 4uovE-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.17A 4uovE-4g7aA:
34.7		 4uovE-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.91A 4uovF-4g7aA:
34.9		 4uovF-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.04A 4uovF-4g7aA:
34.9		 4uovF-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  87
HIS A  89
GLU A 106
VAL A 110
THR A 174
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.23A 4uovF-4g7aA:
34.9		 4uovF-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.16A 4uovF-4g7aA:
34.9		 4uovF-4g7aA:
45.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  67
HIS A  89
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.02A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.24A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.49A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.14A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.95A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.38A 4x5sA-4g7aA:
38.0		 4x5sA-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  67
HIS A  89
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.02A 4x5sB-4g7aA:
38.0		 4x5sB-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.49A 4x5sB-4g7aA:
38.0		 4x5sB-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.13A 4x5sB-4g7aA:
38.0		 4x5sB-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.96A 4x5sB-4g7aA:
38.0		 4x5sB-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.39A 4x5sB-4g7aA:
38.0		 4x5sB-4g7aA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.44A 4xiwA-4g7aA:
28.0
4xiwH-4g7aA:
27.9		 4xiwA-4g7aA:
32.71
4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.25A 4xiwA-4g7aA:
28.0
4xiwH-4g7aA:
27.9		 4xiwA-4g7aA:
32.71
4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.01A 4xiwA-4g7aA:
28.0
4xiwH-4g7aA:
27.9		 4xiwA-4g7aA:
32.71
4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.43A 4xiwA-4g7aA:
28.0
4xiwH-4g7aA:
27.9		 4xiwA-4g7aA:
32.71
4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.12A 4xiwB-4g7aA:
27.9
4xiwE-4g7aA:
28.1		 4xiwB-4g7aA:
32.71
4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.22A 4xiwB-4g7aA:
27.9
4xiwE-4g7aA:
28.1		 4xiwB-4g7aA:
32.71
4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.28A 4xiwC-4g7aA:
28.0		 4xiwC-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.36A 4xiwC-4g7aA:
28.0		 4xiwC-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.26A 4xiwC-4g7aA:
28.0		 4xiwC-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.87A 4xiwC-4g7aA:
28.0		 4xiwC-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 4xiwD-4g7aA:
28.2		 4xiwD-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.24A 4xiwD-4g7aA:
28.2		 4xiwD-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.41A 4xiwD-4g7aA:
28.2		 4xiwD-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.19A 4xiwD-4g7aA:
28.2		 4xiwD-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.89A 4xiwD-4g7aA:
28.2		 4xiwD-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.44A 4xiwE-4g7aA:
28.1		 4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.20A 4xiwE-4g7aA:
28.1		 4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.97A 4xiwE-4g7aA:
28.1		 4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.43A 4xiwE-4g7aA:
28.1		 4xiwE-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 4xiwF-4g7aA:
28.0		 4xiwF-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.49A 4xiwF-4g7aA:
28.0		 4xiwF-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.18A 4xiwF-4g7aA:
28.0		 4xiwF-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.95A 4xiwF-4g7aA:
28.0		 4xiwF-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.36A 4xiwG-4g7aA:
27.9		 4xiwG-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.08A 4xiwH-4g7aA:
27.9		 4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 11 GLN A  87
HIS A  89
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.43A 4xiwH-4g7aA:
27.9		 4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.26A 4xiwH-4g7aA:
27.9		 4xiwH-4g7aA:
32.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.02A 4xiwH-4g7aA:
27.9		 4xiwH-4g7aA:
32.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 LEU A 134
LEU A 138
ILE A 137
GLU A  72
LEU A 105
 None
 0.95A 4y0sA-4g7aA:
undetectable		 4y0sA-4g7aA:
19.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.31A 4ygfA-4g7aA:
30.3		 4ygfA-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.34A 4ygfB-4g7aA:
30.0		 4ygfB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  89
HIS A 108
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.44A 4ygfB-4g7aA:
30.0		 4ygfB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  89
LYS A 112
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.23A 4ygfB-4g7aA:
30.0		 4ygfB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.76A 4ygfB-4g7aA:
30.0		 4ygfB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.43A 4ygfB-4g7aA:
30.0		 4ygfB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.23A 4ygfC-4g7aA:
22.3		 4ygfC-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.28A 4ygfD-4g7aA:
4.7		 4ygfD-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.04A 4ygfD-4g7aA:
4.7		 4ygfD-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.35A 4ygfD-4g7aA:
4.7		 4ygfD-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.30A 4ygfE-4g7aA:
30.6		 4ygfE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  89
LYS A 112
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.27A 4ygfE-4g7aA:
30.6		 4ygfE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.77A 4ygfE-4g7aA:
30.6		 4ygfE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.44A 4ygfE-4g7aA:
30.6		 4ygfE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.24A 4ygfF-4g7aA:
29.9		 4ygfF-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 4ygfF-4g7aA:
29.9		 4ygfF-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.23A 4ygfG-4g7aA:
27.3		 4ygfG-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.06A 4ygfG-4g7aA:
27.3		 4ygfG-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.26A 4ygfH-4g7aA:
30.1		 4ygfH-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 4ygfH-4g7aA:
30.1		 4ygfH-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.39A 4yhaA-4g7aA:
30.2		 4yhaA-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.47A 4yhaB-4g7aA:
29.2		 4yhaB-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 11 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.31A 4yhaC-4g7aA:
30.4		 4yhaC-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 11 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.38A 4yhaD-4g7aA:
29.1		 4yhaD-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 0.38A 4yhaE-4g7aA:
30.5		 4yhaE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  89
HIS A 108
LEU A 173
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 1.48A 4yhaE-4g7aA:
30.5		 4yhaE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
VAL A 120
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.10A 4yhaE-4g7aA:
30.5		 4yhaE-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.62A 4yhaF-4g7aA:
27.2		 4yhaF-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 12 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.30A 4yhaG-4g7aA:
29.9		 4yhaG-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 LYS A 112
VAL A 120
LEU A 173
THR A 174
TRP A 184
 None
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.87A 4yhaG-4g7aA:
29.9		 4yhaG-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 10 HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.39A 4yhaH-4g7aA:
29.9		 4yhaH-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.05A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.22A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  87
HIS A  89
GLU A 106
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
None
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.37A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 GLN A  87
HIS A  89
HIS A  91
GLU A  95
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.32A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.07A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.95A 5c8iA-4g7aA:
30.1		 5c8iA-4g7aA:
34.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 5jn8A-4g7aA:
27.8		 5jn8A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.39A 5jn8A-4g7aA:
27.8		 5jn8A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  89
HIS A  91
GLU A  95
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-3.4A)
 1.08A 5jn8B-4g7aA:
28.2		 5jn8B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.10A 5jn8B-4g7aA:
28.2		 5jn8B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
GLU A 106
HIS A 108
VAL A 110
VAL A 120
TRP A 184
 AZM  A 302 (-4.4A)
None
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
None
 1.47A 5jn8B-4g7aA:
28.2		 5jn8B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 5jn8B-4g7aA:
28.2		 5jn8B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.40A 5jn8B-4g7aA:
28.2		 5jn8B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.35A 5jn8C-4g7aA:
27.7		 5jn8C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.38A 5jn8C-4g7aA:
27.7		 5jn8C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.27A 5jn8D-4g7aA:
27.5		 5jn8D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.42A 5jn8D-4g7aA:
27.5		 5jn8D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.02A 5jn8D-4g7aA:
27.5		 5jn8D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.45A 5jn8D-4g7aA:
27.5		 5jn8D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 5jn9A-4g7aA:
27.8		 5jn9A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.43A 5jn9A-4g7aA:
27.8		 5jn9A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 5jn9B-4g7aA:
28.3		 5jn9B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.46A 5jn9B-4g7aA:
28.3		 5jn9B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.43A 5jn9B-4g7aA:
28.3		 5jn9B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 5jn9C-4g7aA:
27.7		 5jn9C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.41A 5jn9C-4g7aA:
27.7		 5jn9C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 HIS A  91
HIS A 108
LEU A 173
THR A 174
THR A 175
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.49A 5jn9C-4g7aA:
27.7		 5jn9C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.00A 5jn9C-4g7aA:
27.7		 5jn9C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.42A 5jn9C-4g7aA:
27.7		 5jn9C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.29A 5jn9D-4g7aA:
27.5		 5jn9D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.46A 5jnaA-4g7aA:
27.8		 5jnaA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
GLU A  95
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.98A 5jnaA-4g7aA:
27.8		 5jnaA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.44A 5jnaA-4g7aA:
27.8		 5jnaA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
GLU A  95
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.03A 5jnaA-4g7aA:
27.8		 5jnaA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.45A 5jnaB-4g7aA:
28.2		 5jnaB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.02A 5jnaB-4g7aA:
28.2		 5jnaB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.40A 5jnaB-4g7aA:
28.2		 5jnaB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.46A 5jnaB-4g7aA:
28.2		 5jnaB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 11 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.48A 5jnaC-4g7aA:
27.6		 5jnaC-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 5jnaC-4g7aA:
27.6		 5jnaC-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.42A 5jnaC-4g7aA:
27.6		 5jnaC-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 ASN A  62
GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.42A 5jnaD-4g7aA:
27.5		 5jnaD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  67
HIS A  89
HIS A  91
HIS A 108
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.03A 5jnaD-4g7aA:
27.5		 5jnaD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 GLN A  67
HIS A  91
VAL A 110
THR A 174
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.08A 5jnaD-4g7aA:
27.5		 5jnaD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.43A 5jnaD-4g7aA:
27.5		 5jnaD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.93A 5jnaD-4g7aA:
27.5		 5jnaD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 11 GLN A  67
HIS A  91
GLU A  95
VAL A 110
THR A 175
 None
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.4A)
 1.13A 5jncA-4g7aA:
27.8		 5jncA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 11 GLN A  87
HIS A  89
HIS A  91
GLU A  95
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.35A 5jncA-4g7aA:
27.8		 5jncA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.38A 5jncA-4g7aA:
27.8		 5jncA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 11 HIS A  91
GLU A  95
VAL A 110
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.6A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.99A 5jncA-4g7aA:
27.8		 5jncA-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.30A 5jncB-4g7aA:
28.3		 5jncB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.41A 5jncB-4g7aA:
28.3		 5jncB-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 5jncC-4g7aA:
27.7		 5jncC-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.38A 5jncC-4g7aA:
27.7		 5jncC-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.27A 5jncD-4g7aA:
27.5		 5jncD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 9 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.49A 5jncD-4g7aA:
27.5		 5jncD-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.35A 5ku6A-4g7aA:
27.8		 5ku6A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.40A 5ku6A-4g7aA:
27.8		 5ku6A-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 10 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 5ku6B-4g7aA:
28.2		 5ku6B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A 108
HIS A  91
VAL A 120
LEU A 173
THR A 174
THR A 175
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.44A 5ku6B-4g7aA:
28.2		 5ku6B-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.33A 5ku6C-4g7aA:
27.7		 5ku6C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.40A 5ku6C-4g7aA:
27.7		 5ku6C-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 9 GLN A  87
HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
THR A 175
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.31A 5ku6D-4g7aA:
27.5		 5ku6D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 9 GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.41A 5ku6D-4g7aA:
27.5		 5ku6D-4g7aA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 7 GLN A  87
HIS A  89
VAL A 110
LEU A 173
THR A 174
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.35A 5m78A-4g7aA:
29.9		 5m78A-4g7aA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 7 GLN A  87
HIS A  89
VAL A 110
LEU A 173
THR A 175
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.37A 5m78A-4g7aA:
29.9		 5m78A-4g7aA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 7 VAL A 120
LEU A 173
THR A 174
THR A 175
 AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 0.91A 5m78A-4g7aA:
29.9		 5m78A-4g7aA:
14.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.20A 5ogjA-4g7aA:
29.5		 5ogjA-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.32A 5ogjA-4g7aA:
29.5		 5ogjA-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.19A 5ogjB-4g7aA:
28.7		 5ogjB-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.32A 5ogjB-4g7aA:
28.7		 5ogjB-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 5 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.20A 5ohhA-4g7aA:
28.9		 5ohhA-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 5 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 0.32A 5ohhA-4g7aA:
28.9		 5ohhA-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 6 HIS A  89
HIS A  91
LEU A 173
THR A 175
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
 1.19A 5ohhB-4g7aA:
29.5		 5ohhB-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 6 HIS A  89
HIS A 108
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.30A 5ohhB-4g7aA:
29.5		 5ohhB-4g7aA:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 0.36A 5tt3A-4g7aA:
30.0		 5tt3A-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A  91
VAL A 110
LEU A 173
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
None
 1.08A 5tt3A-4g7aA:
30.0		 5tt3A-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 10 HIS A  89
HIS A 108
THR A 174
PRO A 176
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-3.4A)
None
None
 1.33A 5tt3A-4g7aA:
30.0		 5tt3A-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.32A 5tt3B-4g7aA:
27.9		 5tt3B-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		9 / 10 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 0.30A 5tt3C-4g7aA:
30.3		 5tt3C-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 10 HIS A  91
HIS A  89
VAL A 110
LEU A 173
THR A 174
PRO A 177
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.43A 5tt3C-4g7aA:
30.3		 5tt3C-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.32A 5tt3E-4g7aA:
30.4		 5tt3E-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.39A 5tt3F-4g7aA:
29.4		 5tt3F-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		8 / 9 HIS A  89
HIS A  91
HIS A 108
VAL A 110
VAL A 120
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.27A 5tt3G-4g7aA:
29.2		 5tt3G-4g7aA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 8 HIS A  89
HIS A  91
HIS A 108
VAL A 110
LEU A 173
THR A 174
TRP A 184
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 0.41A 5tt3H-4g7aA:
29.7		 5tt3H-4g7aA:
38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		3 / 3 GLU A  95
TRP A 184
HIS A  89
 AZM  A 302 ( 4.6A)
None
ZN  A 301 ( 3.2A)
 1.10A 5xipA-4g7aA:
undetectable		 5xipA-4g7aA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		3 / 3 GLU A 106
TRP A 184
HIS A  89
 None
None
ZN  A 301 ( 3.2A)
 1.12A 5xipA-4g7aA:
undetectable		 5xipA-4g7aA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		5 / 12 ILE A 137
ALA A 141
LEU A 150
ILE A 107
LEU A 201
 None
 0.98A 6a5zL-4g7aA:
undetectable		 6a5zL-4g7aA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 GLN A  67
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.19A 6bbsA-4g7aA:
24.4		 6bbsA-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 TRP A   3
ASN A  62
HIS A  64
GLN A  87
HIS A  89
HIS A  91
LEU A 173
THR A 174
THR A 175
TRP A 184
 None
None
None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.55A 6bbsA-4g7aA:
24.4		 6bbsA-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 TRP A   3
HIS A  64
HIS A  89
THR A 174
THR A 175
TRP A 184
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 1.42A 6bbsA-4g7aA:
24.4		 6bbsA-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		11 / 12 TRP A   3
ASN A  62
GLN A  87
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 None
None
AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.50A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 TRP A   3
GLN A  67
HIS A  91
LEU A 173
THR A 174
THR A 175
 None
None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
 1.17A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 TRP A   3
HIS A  89
HIS A  91
VAL A 120
LEU A 173
THR A 175
PRO A 177
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.22A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 TRP A   3
HIS A  89
LEU A 173
THR A 175
PRO A 177
TRP A 184
 None
ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
None
 1.32A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		7 / 12 TRP A  14
HIS A  89
HIS A  91
VAL A 110
LEU A 173
THR A 175
TRP A 184
 None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
None
 1.50A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		4 / 5 HIS A  64
GLU A  95
HIS A 108
VAL A 120
 None
AZM  A 302 ( 4.6A)
ZN  A 301 ( 3.1A)
AZM  A 302 ( 4.8A)
 0.15A 6bc9A-4g7aA:
30.1		 6bc9A-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		10 / 12 GLN A  87
HIS A  89
HIS A  91
VAL A 110
VAL A 120
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 AZM  A 302 (-4.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 ( 4.8A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 0.34A 6bccA-4g7aA:
30.0		 6bccA-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
LEU A 173
THR A 174
THR A 175
PRO A 177
TRP A 184
 ZN  A 301 ( 3.2A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
None
 1.40A 6bccA-4g7aA:
30.0		 6bccA-4g7aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4g7a CARBONATE
DEHYDRATASE
(Sulfurihydrogeni
bium
sp.
YO3AOP1) 		6 / 12 HIS A  91
VAL A 110
LEU A 173
THR A 174
THR A 175
PRO A 177
 ZN  A 301 ( 3.2A)
AZM  A 302 (-4.7A)
AZM  A 302 (-3.8A)
AZM  A 302 (-3.4A)
AZM  A 302 (-3.4A)
None
 0.94A 6bccA-4g7aA:
30.0		 6bccA-4g7aA:
17.92