SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4g7e UREASE
(Cajanus
cajan) 		5 / 5 HIS B 407
HIS B 492
HIS B 519
HIS B 545
ASP B 633
 NI  B 901 (-3.3A)
KCX  B 490 ( 4.1A)
NI  B 902 (-3.2A)
NI  B 902 (-3.3A)
NI  B 901 (-2.6A)
 0.36A 1e9yB-4g7eB:
63.0		 1e9yB-4g7eB:
40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FWE_C_HAEC989_1
(UREASE)		 4g7e UREASE
(Cajanus
cajan) 		6 / 6 HIS B 407
HIS B 409
HIS B 492
HIS B 519
HIS B 545
ASP B 633
 NI  B 901 (-3.3A)
NI  B 901 (-3.3A)
KCX  B 490 ( 4.1A)
NI  B 902 (-3.2A)
NI  B 902 (-3.3A)
NI  B 901 (-2.6A)
 0.30A 1fweC-4g7eB:
59.7		 1fweC-4g7eB:
40.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		6 / 12 GLY B 723
ALA B 703
ASP B 704
ILE B 357
GLY B 700
ILE B 359
 None
 1.47A 1hshA-4g7eB:
undetectable		 1hshA-4g7eB:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 LEU B 506
LEU B 489
ALA B 484
ALA B 486
VAL B 516
 None
KCX  B 490 ( 4.0A)
None
None
None
 1.23A 1kt4A-4g7eB:
undetectable		 1kt4A-4g7eB:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ASP B 183
THR B 262
GLY B 260
ALA B 257
ALA B 258
 None
 1.27A 1nw5A-4g7eB:
undetectable		 1nw5A-4g7eB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.96A 1rxcB-4g7eB:
undetectable		 1rxcB-4g7eB:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.95A 1rxcI-4g7eB:
undetectable		 1rxcI-4g7eB:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.94A 1rxcK-4g7eB:
undetectable		 1rxcK-4g7eB:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.82A 1sdtB-4g7eB:
undetectable		 1sdtB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.82A 1sdvB-4g7eB:
undetectable		 1sdvB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 GLU B 312
ARG B 276
SER B 169
VAL B 320
HIS B 170
 None
 1.50A 1x70B-4g7eB:
undetectable		 1x70B-4g7eB:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 GLY B 429
MET B 487
VAL B 765
THR B 426
ILE B 404
 None
 1.31A 1z95A-4g7eB:
undetectable		 1z95A-4g7eB:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.79A 2avoB-4g7eB:
undetectable		 2avoB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		6 / 12 GLY B 368
ALA B 355
ASP B 356
VAL B 399
ILE B 341
ILE B 346
 None
 1.33A 2avoB-4g7eB:
undetectable		 2avoB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.81A 2avsB-4g7eB:
undetectable		 2avsB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.83A 2bpxB-4g7eB:
undetectable		 2bpxB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 THR B 574
PRO B 576
PRO B 573
 None
 0.89A 2d55C-4g7eB:
undetectable		 2d55C-4g7eB:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.85A 2o4kB-4g7eB:
undetectable		 2o4kB-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		4 / 7 ALA B 613
THR B 614
ALA B 617
PRO B 555
 None
 0.58A 2ql8A-4g7eB:
undetectable
2ql8B-4g7eB:
undetectable		 2ql8A-4g7eB:
10.60
2ql8B-4g7eB:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.82A 2r5pB-4g7eB:
undetectable		 2r5pB-4g7eB:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 ASP B 704
LEU B 702
VAL B 694
PHE B 764
THR B 425
 None
 1.08A 2w9gA-4g7eB:
undetectable		 2w9gA-4g7eB:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 ASP B 704
LEU B 702
VAL B 694
PHE B 764
THR B 425
 None
 1.04A 2w9hA-4g7eB:
undetectable		 2w9hA-4g7eB:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 MET B 637
GLU B 547
ASP B 556
 CME  B 592 ( 4.9A)
None
None
 1.02A 3a25A-4g7eB:
undetectable		 3a25A-4g7eB:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 MET B 637
GLU B 493
ASN B 524
 CME  B 592 ( 4.9A)
None
None
 0.94A 3a27A-4g7eB:
undetectable		 3a27A-4g7eB:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 LEU B 427
GLY B 429
ILE B 686
TYR B 410
ASN B 463
 None
 0.95A 3eeoA-4g7eB:
undetectable		 3eeoA-4g7eB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.87A 3ekxB-4g7eB:
undetectable		 3ekxB-4g7eB:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 ASP B 704
LEU B 702
VAL B 694
PHE B 764
THR B 425
 None
 1.03A 3frbX-4g7eB:
undetectable		 3frbX-4g7eB:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 9 ASP B 704
LEU B 702
VAL B 694
PHE B 764
THR B 425
 None
 0.97A 3freX-4g7eB:
undetectable		 3freX-4g7eB:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 9 LEU B 462
THR B 426
GLY B 695
ALA B 401
ILE B 644
 None
 1.31A 3jusB-4g7eB:
undetectable		 3jusB-4g7eB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.94A 3lzvB-4g7eB:
undetectable		 3lzvB-4g7eB:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 SER B 631
ILE B 558
CYH B 561
GLU B 618
LEU B 621
 None
 1.33A 3m0wC-4g7eB:
undetectable
3m0wD-4g7eB:
1.6
3m0wE-4g7eB:
undetectable
3m0wF-4g7eB:
1.4		 3m0wC-4g7eB:
9.13
3m0wD-4g7eB:
9.13
3m0wE-4g7eB:
9.13
3m0wF-4g7eB:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 PHE B 536
ILE B 533
THR B 543
ILE B 557
VAL B 529
 None
 1.07A 3me6A-4g7eB:
undetectable		 3me6A-4g7eB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.91A 3nujA-4g7eB:
undetectable		 3nujA-4g7eB:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 7 GLY B 551
GLY B 552
LEU B 523
PHE B 605
 NI  B 902 ( 4.9A)
None
None
None
 0.67A 3o9mA-4g7eB:
undetectable		 3o9mA-4g7eB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 VAL B 784
PHE B 690
GLY B 488
ASN B 517
ILE B 482
 None
 1.27A 3owxA-4g7eB:
undetectable
3owxB-4g7eB:
undetectable		 3owxA-4g7eB:
14.64
3owxB-4g7eB:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 ILE B 364
ILE B 359
VAL B 697
ILE B 721
 None
 0.86A 3p4wC-4g7eB:
undetectable		 3p4wC-4g7eB:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tA-4g7eB:
undetectable		 3w9tA-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 6 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.00A 3w9tB-4g7eB:
undetectable		 3w9tB-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tC-4g7eB:
undetectable		 3w9tC-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tD-4g7eB:
undetectable		 3w9tD-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 6 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tE-4g7eB:
undetectable		 3w9tE-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 6 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tF-4g7eB:
undetectable		 3w9tF-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 ASP B 348
GLY B 695
TYR B 349
GLU B 698
 None
 1.01A 3w9tG-4g7eB:
undetectable		 3w9tG-4g7eB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 ASN B 225
GLU B 175
ARG B 184
 None
 1.04A 3wxoA-4g7eB:
undetectable		 3wxoA-4g7eB:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 THR B 808
ILE B 807
LYS B 559
GLU B 563
 None
 1.38A 4ac9C-4g7eB:
2.9		 4ac9C-4g7eB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 THR B 808
ILE B 807
LYS B 559
GLU B 563
 None
 1.39A 4acaC-4g7eB:
2.9		 4acaC-4g7eB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4g7e UREASE
(Cajanus
cajan) 		4 / 4 ILE B 620
HIS B 622
MET B 624
ARG B 672
 None
 1.48A 4acbB-4g7eB:
0.1
4acbC-4g7eB:
1.8		 4acbB-4g7eB:
20.09
4acbC-4g7eB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 THR B 808
ILE B 807
LYS B 559
GLU B 563
 None
 1.42A 4acbC-4g7eB:
undetectable		 4acbC-4g7eB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ALA B 355
VAL B 399
ILE B 341
GLY B 358
ILE B 346
 None
 0.92A 4dqfA-4g7eB:
undetectable		 4dqfA-4g7eB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.96A 4e1vA-4g7eB:
undetectable		 4e1vA-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.93A 4e1vC-4g7eB:
undetectable		 4e1vC-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.95A 4e1vD-4g7eB:
undetectable		 4e1vD-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 0.94A 4e1vE-4g7eB:
undetectable		 4e1vE-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 1.00A 4e1vG-4g7eB:
undetectable		 4e1vG-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 THR B 385
GLY B 326
ILE B 321
VAL B 320
 None
 1.00A 4e1vH-4g7eB:
undetectable		 4e1vH-4g7eB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 ASN B 343
VAL B 391
ILE B 321
ALA B 196
 None
 0.93A 4eyzA-4g7eB:
undetectable		 4eyzA-4g7eB:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 ASN B 343
VAL B 391
ILE B 321
ALA B 196
 None
 0.94A 4eyzB-4g7eB:
undetectable		 4eyzB-4g7eB:
16.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H9M_A_HAEA929_1
(UREASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 5 HIS B 407
HIS B 492
HIS B 519
HIS B 545
ASP B 633
 NI  B 901 (-3.3A)
KCX  B 490 ( 4.1A)
NI  B 902 (-3.2A)
NI  B 902 (-3.3A)
NI  B 901 (-2.6A)
 0.24A 4h9mA-4g7eB:
62.9		 4h9mA-4g7eB:
83.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 LYS B 709
PRO B 710
SER B 711
 None
 0.23A 4k50I-4g7eB:
undetectable		 4k50I-4g7eB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 SER B 370
ASP B 356
VAL B 320
THR B 314
 None
 1.09A 4lnwA-4g7eB:
undetectable		 4lnwA-4g7eB:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 LEU B  24
LEU B  38
ARG B  29
PRO B  99
VAL B  81
 None
None
MG  B 903 (-2.7A)
None
None
 1.15A 4mk4B-4g7eB:
undetectable		 4mk4B-4g7eB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4g7e UREASE
(Cajanus
cajan) 		4 / 8 ILE B 541
HIS B 519
PHE B 536
THR B 522
 None
NI  B 902 (-3.2A)
None
None
 0.90A 4n16A-4g7eB:
undetectable		 4n16A-4g7eB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 GLY B 429
MET B 487
VAL B 765
THR B 426
ILE B 404
 None
 1.31A 4okwA-4g7eB:
undetectable		 4okwA-4g7eB:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 MET B 487
VAL B 765
THR B 426
ILE B 404
VAL B 694
 None
 1.32A 4okwA-4g7eB:
undetectable		 4okwA-4g7eB:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 THR B 442
GLY B 468
HIS B 409
ASN B 517
SER B 634
 KCX  B 490 ( 3.5A)
KCX  B 490 ( 4.9A)
NI  B 901 (-3.3A)
None
None
 1.31A 4pooA-4g7eB:
2.0		 4pooA-4g7eB:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvlV-4g7eB:
undetectable
4qvlb-4g7eB:
undetectable		 4qvlV-4g7eB:
14.55
4qvlb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvlH-4g7eB:
undetectable
4qvlN-4g7eB:
undetectable		 4qvlH-4g7eB:
14.55
4qvlN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvmV-4g7eB:
undetectable
4qvmb-4g7eB:
undetectable		 4qvmV-4g7eB:
14.55
4qvmb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvmH-4g7eB:
undetectable
4qvmN-4g7eB:
undetectable		 4qvmH-4g7eB:
14.55
4qvmN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvpV-4g7eB:
undetectable
4qvpb-4g7eB:
undetectable		 4qvpV-4g7eB:
14.55
4qvpb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvpH-4g7eB:
undetectable
4qvpN-4g7eB:
undetectable		 4qvpH-4g7eB:
14.55
4qvpN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvqV-4g7eB:
undetectable
4qvqb-4g7eB:
undetectable		 4qvqV-4g7eB:
14.55
4qvqb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qvqH-4g7eB:
undetectable
4qvqN-4g7eB:
undetectable		 4qvqH-4g7eB:
14.55
4qvqN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.47A 4qvvV-4g7eB:
undetectable
4qvvb-4g7eB:
undetectable		 4qvvV-4g7eB:
14.55
4qvvb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4g7e UREASE
(Cajanus
cajan) 		5 / 8 THR B 438
GLY B 430
GLY B 429
VAL B 408
ASP B 405
 None
 1.34A 4qvvK-4g7eB:
undetectable
4qvvL-4g7eB:
undetectable		 4qvvK-4g7eB:
12.02
4qvvL-4g7eB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 10 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qvvH-4g7eB:
undetectable
4qvvN-4g7eB:
undetectable		 4qvvH-4g7eB:
14.55
4qvvN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4g7e UREASE
(Cajanus
cajan) 		5 / 8 THR B 438
GLY B 430
GLY B 429
VAL B 408
ASP B 405
 None
 1.33A 4qvvY-4g7eB:
undetectable
4qvvZ-4g7eB:
undetectable		 4qvvY-4g7eB:
12.02
4qvvZ-4g7eB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qvwV-4g7eB:
undetectable
4qvwb-4g7eB:
undetectable		 4qvwV-4g7eB:
14.55
4qvwb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qvwH-4g7eB:
undetectable
4qvwN-4g7eB:
undetectable		 4qvwH-4g7eB:
14.55
4qvwN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qvyH-4g7eB:
undetectable
4qvyN-4g7eB:
undetectable		 4qvyH-4g7eB:
14.55
4qvyN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qw0V-4g7eB:
undetectable
4qw0b-4g7eB:
undetectable		 4qw0V-4g7eB:
14.55
4qw0b-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qw0H-4g7eB:
undetectable
4qw0N-4g7eB:
undetectable		 4qw0H-4g7eB:
14.55
4qw0N-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.44A 4qw1V-4g7eB:
undetectable
4qw1b-4g7eB:
undetectable		 4qw1V-4g7eB:
14.55
4qw1b-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 4qw1H-4g7eB:
undetectable
4qw1N-4g7eB:
undetectable		 4qw1H-4g7eB:
14.55
4qw1N-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qw3V-4g7eB:
undetectable
4qw3b-4g7eB:
undetectable		 4qw3V-4g7eB:
14.55
4qw3b-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 4qw3H-4g7eB:
undetectable
4qw3N-4g7eB:
undetectable		 4qw3H-4g7eB:
14.55
4qw3N-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.43A 4qwuV-4g7eB:
undetectable
4qwub-4g7eB:
undetectable		 4qwuV-4g7eB:
14.55
4qwub-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.44A 4qwuH-4g7eB:
undetectable
4qwuN-4g7eB:
undetectable		 4qwuH-4g7eB:
14.55
4qwuN-4g7eB:
13.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 4g7e UREASE
(Cajanus
cajan) 		6 / 6 HIS B 407
HIS B 409
HIS B 492
HIS B 519
HIS B 545
ASP B 633
 NI  B 901 (-3.3A)
NI  B 901 (-3.3A)
KCX  B 490 ( 4.1A)
NI  B 902 (-3.2A)
NI  B 902 (-3.3A)
NI  B 901 (-2.6A)
 0.22A 4ubpC-4g7eB:
63.7		 4ubpC-4g7eB:
40.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 ASP B 633
ARG B 639
ILE B 615
ARG B 646
THR B 571
 NI  B 901 (-2.6A)
None
None
None
None
 1.39A 4urnB-4g7eB:
undetectable		 4urnB-4g7eB:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 MET B 376
ASP B 356
PHE B 306
 None
 1.06A 4xeyA-4g7eB:
undetectable		 4xeyA-4g7eB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 MET B 376
ASP B 356
PHE B 306
 None
 1.03A 4xeyB-4g7eB:
undetectable		 4xeyB-4g7eB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.47A 5bxnV-4g7eB:
undetectable
5bxnb-4g7eB:
undetectable		 5bxnV-4g7eB:
14.55
5bxnb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.48A 5bxnH-4g7eB:
undetectable
5bxnN-4g7eB:
undetectable		 5bxnH-4g7eB:
14.55
5bxnN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 9 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 5cz7V-4g7eB:
undetectable
5cz7b-4g7eB:
undetectable		 5cz7V-4g7eB:
14.55
5cz7b-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 5cz7H-4g7eB:
undetectable
5cz7N-4g7eB:
undetectable		 5cz7H-4g7eB:
14.55
5cz7N-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 5d0xV-4g7eB:
undetectable
5d0xb-4g7eB:
undetectable		 5d0xV-4g7eB:
14.55
5d0xb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 5d0xH-4g7eB:
undetectable
5d0xN-4g7eB:
undetectable		 5d0xH-4g7eB:
14.55
5d0xN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 CYH B 237
ALA B 240
PHE B 182
GLU B 175
VAL B 244
 None
 1.26A 5hw4B-4g7eB:
undetectable		 5hw4B-4g7eB:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 GLY B 310
ASP B 311
ASN B 372
 None
 0.62A 5jglA-4g7eB:
undetectable		 5jglA-4g7eB:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 5l5fV-4g7eB:
undetectable
5l5fb-4g7eB:
undetectable		 5l5fV-4g7eB:
14.55
5l5fb-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 5l5fH-4g7eB:
undetectable
5l5fN-4g7eB:
undetectable		 5l5fH-4g7eB:
14.55
5l5fN-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.46A 5l66V-4g7eB:
undetectable
5l66b-4g7eB:
undetectable		 5l66V-4g7eB:
14.55
5l66b-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4g7e UREASE
(Cajanus
cajan) 		5 / 11 SER B 634
THR B 442
THR B 441
THR B 438
THR B 571
 None
KCX  B 490 ( 3.5A)
None
None
None
 1.45A 5l66H-4g7eB:
undetectable
5l66N-4g7eB:
undetectable		 5l66H-4g7eB:
14.55
5l66N-4g7eB:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 LYS B 709
TRP B 708
SER B 711
 None
 1.06A 5nwwA-4g7eB:
undetectable		 5nwwA-4g7eB:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4g7e UREASE
(Cajanus
cajan) 		4 / 4 GLU B 618
THR B 571
THR B 522
LEU B 589
 None
 1.38A 5v96B-4g7eB:
3.3		 5v96B-4g7eB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 GLN B  42
ALA B  40
ILE B  60
VAL B  94
PHE B  87
 None
 1.25A 5vlmG-4g7eB:
undetectable		 5vlmG-4g7eB:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ILE B 610
GLY B 551
MET B 637
ALA B 636
ASP B 619
 None
NI  B 902 ( 4.9A)
CME  B 592 ( 4.9A)
CME  B 592 ( 3.9A)
None
 1.17A 5x66A-4g7eB:
undetectable
5x66B-4g7eB:
undetectable		 5x66A-4g7eB:
16.96
5x66B-4g7eB:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 4g7e UREASE
(Cajanus
cajan) 		4 / 5 HIS B 251
ASN B 160
VAL B 157
LEU B 155
 None
 1.47A 5xdhD-4g7eB:
undetectable		 5xdhD-4g7eB:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4g7e UREASE
(Cajanus
cajan) 		3 / 3 PHE B 124
ARG B  68
GLN B  69
 None
 1.17A 6g1pB-4g7eB:
undetectable		 6g1pB-4g7eB:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4g7e UREASE
(Cajanus
cajan) 		5 / 12 ILE B  43
ILE B  39
VAL B  94
THR B  95
ILE B  96
 None
 1.12A 6hlpA-4g7eB:
undetectable		 6hlpA-4g7eB:
19.48