SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 11 LEU S 224
ARG S 226
VAL S 196
LEU S 137
ASP S 136
 None
 1.23A 2q6hA-4g7vS:
undetectable		 2q6hA-4g7vS:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 11 TYR S 150
ARG S 223
LEU S 137
GLN S 147
PHE S 149
 None
 1.05A 3qelA-4g7vS:
undetectable
3qelB-4g7vS:
undetectable		 3qelA-4g7vS:
18.54
3qelB-4g7vS:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 10 TYR S 150
ARG S 223
LEU S 137
GLN S 147
PHE S 149
 None
 1.02A 4pe5A-4g7vS:
undetectable
4pe5B-4g7vS:
undetectable		 4pe5A-4g7vS:
13.40
4pe5B-4g7vS:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 10 TYR S 150
ARG S 223
LEU S 137
GLN S 147
PHE S 149
 None
 1.04A 4pe5C-4g7vS:
undetectable
4pe5D-4g7vS:
undetectable		 4pe5C-4g7vS:
13.40
4pe5D-4g7vS:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 6 LYS S 175
GLY S 173
TYR S 172
ALA S 171
 None
 1.11A 4yshB-4g7vS:
undetectable		 4yshB-4g7vS:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 11 TYR S 150
ARG S 223
LEU S 137
GLN S 147
PHE S 149
 None
 1.10A 5ewjA-4g7vS:
undetectable
5ewjB-4g7vS:
undetectable		 5ewjA-4g7vS:
18.56
5ewjB-4g7vS:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		5 / 12 TYR S 150
ARG S 223
LEU S 137
GLN S 147
PHE S 149
 None
 1.12A 5ewjC-4g7vS:
undetectable
5ewjD-4g7vS:
undetectable		 5ewjC-4g7vS:
18.56
5ewjD-4g7vS:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4g7v VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE
(Ciona
intestinalis) 		4 / 7 THR S 193
ARG S 226
ASP S 129
LEU S 157
 None
 1.08A 5uxcA-4g7vS:
2.2		 5uxcA-4g7vS:
20.41