SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4g7x PUTATIVE
UNCHARACTERIZED
PROTEIN
TOLA PROTEIN

(Vibrio
cholerae)
4 / 8 LEU B 351
THR B 352
GLY B 315
THR A  10
None
0.69A 3jusA-4g7xB:
undetectable
3jusA-4g7xB:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4g7x PUTATIVE
UNCHARACTERIZED
PROTEIN
TOLA PROTEIN

(Vibrio
cholerae)
4 / 8 LEU B 351
THR B 352
GLY B 315
THR A  10
None
0.69A 3jusA-4g7xB:
undetectable
3jusA-4g7xB:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)
4g7x PUTATIVE
UNCHARACTERIZED
PROTEIN

(Vibrio
cholerae)
4 / 5 GLU A  83
SER A  81
PRO A  22
SER A  21
None
1.43A 4k17B-4g7xA:
undetectable
4k17B-4g7xA:
9.73