SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g88 OUTER MEMBRANE
PROTEIN OMP38
(Acinetobacter
baumannii) 		5 / 10 ALA A 253
LEU A 305
SER A 306
ALA A 333
ILE A 249
 None
 1.08A 1g5yC-4g88A:
undetectable		 1g5yC-4g88A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 4g88 OUTER MEMBRANE
PROTEIN OMP38
(Acinetobacter
baumannii) 		3 / 3 ARG A 330
ARG A 286
ILE A 316
 None
API  A 401 (-3.0A)
None
 0.83A 4b7qA-4g88A:
undetectable		 4b7qA-4g88A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4g88 OUTER MEMBRANE
PROTEIN OMP38
(Acinetobacter
baumannii) 		3 / 3 ARG A 330
ARG A 286
ILE A 316
 None
API  A 401 (-3.0A)
None
 0.89A 4b7qC-4g88A:
undetectable		 4b7qC-4g88A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 4g88 OUTER MEMBRANE
PROTEIN OMP38
(Acinetobacter
baumannii) 		3 / 3 ARG A 339
LYS A 255
GLU A 258
 None
 0.64A 5d0yA-4g88A:
undetectable		 5d0yA-4g88A:
19.77