SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4g8s NITROREDUCTASE
FAMILY PROTEIN
(Geobacter
sulfurreducens) 		4 / 6 PHE A  16
ALA A  79
LEU A  83
ALA A  86
 None
FMN  A 300 (-3.4A)
None
None
 0.97A 2vcvB-4g8sA:
undetectable		 2vcvB-4g8sA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4g8s NITROREDUCTASE
FAMILY PROTEIN
(Geobacter
sulfurreducens) 		5 / 11 ALA A 115
PHE A  47
TYR A 108
GLN A 106
PHE A 132
 None
None
None
None
FMN  A 300 (-3.7A)
 1.45A 3bszF-4g8sA:
undetectable		 3bszF-4g8sA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4g8s NITROREDUCTASE
FAMILY PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 LEU A  30
VAL A 181
LEU A 128
LEU A 159
 None
 0.98A 4l1xA-4g8sA:
undetectable		 4l1xA-4g8sA:
19.27