SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4g97 RESPONSE REGULATOR
RECEIVER
(Brucella
abortus) 		5 / 12 ALA A 253
GLN A 252
LEU A 249
LEU A 254
ILE A 144
 None
 0.95A 2aclA-4g97A:
undetectable
2aclE-4g97A:
undetectable		 2aclA-4g97A:
23.51
2aclE-4g97A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4g97 RESPONSE REGULATOR
RECEIVER
(Brucella
abortus) 		5 / 12 MET A 245
VAL A 104
ARG A  53
LEU A 249
ILE A 192
 None
 1.14A 3mnoA-4g97A:
undetectable		 3mnoA-4g97A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4g97 RESPONSE REGULATOR
RECEIVER
(Brucella
abortus) 		5 / 12 MET A 245
VAL A 104
ARG A  53
LEU A 249
ILE A 192
 None
 1.12A 3mnpA-4g97A:
undetectable		 3mnpA-4g97A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 4g97 RESPONSE REGULATOR
RECEIVER
(Brucella
abortus) 		4 / 7 MET A 143
LEU A 194
ALA A 190
VAL A 215
 None
 0.92A 4ik7A-4g97A:
undetectable		 4ik7A-4g97A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 4g97 RESPONSE REGULATOR
RECEIVER
(Brucella
abortus) 		5 / 8 ALA A 190
VAL A 215
PHE A 217
GLY A 200
ALA A 203
 None
 1.07A 4zjzA-4g97A:
5.1		 4zjzA-4g97A:
19.33