SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 9 ILE A 170
LEU A 125
VAL A 112
GLY A 113
LEU A 102
 None
 0.81A 1e7aB-4g9bA:
undetectable		 1e7aB-4g9bA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 9 ILE A 170
LEU A 125
VAL A 112
GLY A 113
LEU A 102
 None
 0.93A 1e7bA-4g9bA:
undetectable		 1e7bA-4g9bA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 7 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.05A 2eimP-4g9bA:
undetectable
2eimW-4g9bA:
undetectable		 2eimP-4g9bA:
21.31
2eimW-4g9bA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 5 LEU A  10
ASP A 172
LEU A  89
HIS A  21
 CL  A 303 (-4.0A)
MG  A 301 (-2.6A)
None
SO4  A 307 (-4.0A)
 1.14A 2jfaA-4g9bA:
undetectable		 2jfaA-4g9bA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 ILE A 180
ALA A 166
GLY A   5
GLY A 169
PRO A 163
 None
 1.08A 2okcA-4g9bA:
undetectable		 2okcA-4g9bA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 ILE A 180
ALA A 166
GLY A   5
GLY A 169
PRO A 163
 None
 1.02A 2y7hB-4g9bA:
undetectable		 2y7hB-4g9bA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 ILE A 180
ALA A 166
GLY A   5
GLY A 169
PRO A 163
 None
 1.02A 2y7hC-4g9bA:
undetectable		 2y7hC-4g9bA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 7 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.05A 3asnP-4g9bA:
undetectable
3asnW-4g9bA:
undetectable		 3asnP-4g9bA:
21.31
3asnW-4g9bA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 6 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.04A 3wg7C-4g9bA:
undetectable
3wg7J-4g9bA:
undetectable		 3wg7C-4g9bA:
21.31
3wg7J-4g9bA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 6 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.04A 3wg7P-4g9bA:
undetectable
3wg7W-4g9bA:
undetectable		 3wg7P-4g9bA:
21.31
3wg7W-4g9bA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 ASP A  11
ILE A  14
LEU A  95
SER A  85
GLN A  23
 MG  A 301 ( 4.8A)
None
None
None
None
 1.16A 4djfB-4g9bA:
undetectable		 4djfB-4g9bA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 9 ALA A 115
GLY A   5
ILE A 168
GLY A 169
ILE A 170
 None
 1.06A 4eatB-4g9bA:
2.8		 4eatB-4g9bA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 GLY A 176
GLU A 171
ALA A 175
ASN A 145
ILE A 152
 None
MG  A 301 ( 4.1A)
None
None
None
 1.35A 4pb1A-4g9bA:
undetectable		 4pb1A-4g9bA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		5 / 12 ALA A 126
LEU A 130
PHE A 133
ALA A 140
ALA A 121
 SO4  A 306 ( 4.9A)
None
None
None
None
 1.14A 4pclA-4g9bA:
undetectable		 4pclA-4g9bA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 7 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.00A 5b1bP-4g9bA:
undetectable
5b1bW-4g9bA:
undetectable		 5b1bP-4g9bA:
21.31
5b1bW-4g9bA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 6 SER A 183
GLY A 169
MET A 185
ILE A 152
 None
 0.95A 5j4nA-4g9bA:
undetectable		 5j4nA-4g9bA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		4 / 5 LEU A 114
PHE A   8
PHE A 134
LEU A 125
 None
 1.08A 5x1bP-4g9bA:
undetectable		 5x1bP-4g9bA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 4g9b BETA-PHOSPHOGLUCOMUT
ASE
(Escherichia
coli) 		3 / 3 LEU A  74
LEU A  57
ARG A  71
 None
 0.70A 6fgcA-4g9bA:
undetectable		 6fgcA-4g9bA:
21.00