SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4g9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.24A 1a4gB-4g9qA:
undetectable		 1a4gB-4g9qA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		4 / 6 HIS A 201
ILE A 186
ALA A  61
VAL A 218
 None
 1.04A 1hk1A-4g9qA:
undetectable		 1hk1A-4g9qA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 190
ALA A  61
ARG A 179
LEU A 210
ILE A 186
 None
 0.94A 2d0kB-4g9qA:
undetectable		 2d0kB-4g9qA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.21A 2htqA-4g9qA:
undetectable		 2htqA-4g9qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		4 / 8 GLN A  36
ARG A  51
TRP A  44
THR A  58
 None
 1.43A 2vxaF-4g9qA:
undetectable
2vxaG-4g9qA:
undetectable
2vxaI-4g9qA:
undetectable		 2vxaF-4g9qA:
15.81
2vxaG-4g9qA:
15.81
2vxaI-4g9qA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		4 / 6 HIS A 221
ALA A  61
ALA A  60
THR A  91
 None
 0.96A 2xfhA-4g9qA:
undetectable		 2xfhA-4g9qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 223
LEU A 222
VAL A 218
ALA A 205
LEU A 202
 None
 0.95A 3ozuA-4g9qA:
undetectable		 3ozuA-4g9qA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.35A 4cpnB-4g9qA:
undetectable		 4cpnB-4g9qA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		4 / 8 ILE A 120
ILE A  88
ALA A  78
GLU A  80
 None
 0.81A 4jltA-4g9qA:
undetectable		 4jltA-4g9qA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		3 / 3 LYS A  84
PRO A  85
SER A  86
 None
 0.29A 4k50I-4g9qA:
1.3		 4k50I-4g9qA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.29A 4mwrA-4g9qA:
undetectable		 4mwrA-4g9qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.29A 4mwxA-4g9qA:
undetectable		 4mwxA-4g9qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.26A 5l17A-4g9qA:
undetectable		 5l17A-4g9qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A 179
VAL A  83
GLY A  82
SER A  55
LEU A  56
 None
 1.38A 6ci6A-4g9qA:
undetectable		 6ci6A-4g9qA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		3 / 3 TYR A  74
ASP A  76
GLN A  77
 None
 0.80A 6g1pA-4g9qA:
undetectable		 6g1pA-4g9qA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4g9q 4-CARBOXYMUCONOLACTO
NE DECARBOXYLASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  46
GLU A 217
ARG A  54
GLU A 213
ALA A 238
 None
 1.32A 6hcxA-4g9qA:
undetectable		 6hcxA-4g9qA:
17.45