SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EIZ_A_SAMA301_1 (FTSJ)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	ASP A 91 ASP A 96 ASP A 84	None	0.62A	1eizA-4gaoA: undetectable	1eizA-4gaoA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EJ0_A_SAMA301_1 (FTSJ)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	ASP A 91 ASP A 96 ASP A 84	None	0.59A	1ej0A-4gaoA: undetectable	1ej0A-4gaoA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_1 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	5 / 12	ALA A 106 ALA A 111 PHE A 117 PHE A 160 LEU A 173	None	1.21A	2nyrA-4gaoA: undetectable	2nyrA-4gaoA: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DOU_A_SAMA1_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	ASP A 91 ASP A 96 ASP A 84	None	0.54A	3douA-4gaoA: undetectable	3douA-4gaoA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	3 / 3	ARG A 189 PHE A 160 LEU A 148	None	0.58A	5x1bC-4gaoA: undetectable	5x1bC-4gaoA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_C_CHDC307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4gao	DCN1-LIKE PROTEIN 2 (Homo sapiens)	4 / 6	LYS A 155 GLN A 159 LEU A 186 PHE A 190	None	1.35A	6nmpC-4gaoA: undetectable 6nmpJ-4gaoA: undetectable	6nmpC-4gaoA: 20.08 6nmpJ-4gaoA: 14.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EIZ_A_SAMA301_1","FTSJ","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",3,"ASP A  91;ASP A  96;ASP A  84","None","0.62A","1eizA-4gaoA:undetectable","1eizA-4gaoA:21.80"],["1EJ0_A_SAMA301_1","FTSJ","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",3,"ASP A  91;ASP A  96;ASP A  84","None","0.59A","1ej0A-4gaoA:undetectable","1ej0A-4gaoA:21.80"],["2NYR_B_SVRB401_1","NAD-DEPENDENT DEACETYLASE SIRTUIN-5;NAD-DEPENDENT DEACETYLASE SIRTUIN-5","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",5,"ALA A 106;ALA A 111;PHE A 117;PHE A 160;LEU A 173","None","1.21A","2nyrA-4gaoA:undetectable","2nyrA-4gaoA:21.67"],["3DOU_A_SAMA1_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",3,"ASP A  91;ASP A  96;ASP A  84","None","0.54A","3douA-4gaoA:undetectable","3douA-4gaoA:23.35"],["5X1B_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",3,"ARG A 189;PHE A 160;LEU A 148","None","0.58A","5x1bC-4gaoA:undetectable","5x1bC-4gaoA:20.08"],["6NMP_C_CHDC307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4gao","DCN1-LIKE PROTEIN 2","Homo sapiens",4,"LYS A 155;GLN A 159;LEU A 186;PHE A 190","None","1.35A","6nmpC-4gaoA:undetectable;6nmpJ-4gaoA:undetectable","6nmpC-4gaoA:20.08;6nmpJ-4gaoA:14.38"]]