SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		3 / 3 LEU A 191
SER A 239
ASN A 244
 None
 0.78A 1bx4A-4gbaA:
undetectable		 1bx4A-4gbaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 12 PHE A 270
ASN A 231
GLY A 237
SER A 239
ILE A 235
 None
 1.09A 2e7fA-4gbaA:
undetectable		 2e7fA-4gbaA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 12 PHE A 270
ASN A 231
GLY A 237
SER A 239
ILE A 235
 None
 1.12A 2e7fB-4gbaA:
undetectable		 2e7fB-4gbaA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 12 PHE A 270
ASN A 231
GLY A 237
SER A 239
ILE A 235
 None
 1.10A 2ogyA-4gbaA:
undetectable		 2ogyA-4gbaA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 12 PHE A 270
ASN A 231
GLY A 237
SER A 239
ILE A 235
 None
 1.11A 2ogyB-4gbaA:
undetectable		 2ogyB-4gbaA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 12 PHE A 270
ASN A 231
GLY A 237
SER A 239
ILE A 235
 None
 1.12A 2ycjA-4gbaA:
undetectable		 2ycjA-4gbaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G59_A_ACTA306_0
(FMN
ADENYLYLTRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		4 / 5 SER A 233
PHE A 227
ILE A 235
TRP A 224
 None
 0.86A 3g59A-4gbaA:
undetectable		 3g59A-4gbaA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		3 / 3 TYR A  98
ASP A 160
ASP A 117
 None
 0.57A 3r24A-4gbaA:
undetectable		 3r24A-4gbaA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		5 / 10 PHE A 249
PHE A 246
ILE A 253
GLY A 254
PHE A 273
 None
 1.27A 3t3rD-4gbaA:
undetectable		 3t3rD-4gbaA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		4 / 7 ASN A 244
PHE A 187
TRP A 209
PHE A 213
 None
 0.91A 4v32A-4gbaA:
undetectable		 4v32A-4gbaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		4 / 7 ASN A 244
PHE A 187
TRP A 209
PHE A 213
 None
 1.02A 4v32B-4gbaA:
undetectable		 4v32B-4gbaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4gba DCN1-LIKE PROTEIN 3
(Homo
sapiens) 		4 / 7 ASN A 244
PHE A 187
TRP A 209
PHE A 213
 None
 1.01A 4v32C-4gbaA:
undetectable		 4v32C-4gbaA:
20.18