SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gbf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		3 / 3 GLU A 406
ASN A 422
TRP A 424
 None
 1.26A 1r15C-4gbfA:
undetectable		 1r15C-4gbfA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		3 / 3 GLU A 406
ASN A 422
TRP A 424
 None
 1.25A 1r15D-4gbfA:
undetectable		 1r15D-4gbfA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		3 / 3 GLU A 406
ASN A 422
TRP A 424
 None
 1.25A 1r15E-4gbfA:
undetectable		 1r15E-4gbfA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		3 / 3 GLU A 406
ASN A 422
TRP A 424
 None
 1.28A 1r15F-4gbfA:
undetectable		 1r15F-4gbfA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		4 / 5 HIS A 533
SER A 504
SER A 458
VAL A 469
 None
 1.26A 4a99D-4gbfA:
undetectable		 4a99D-4gbfA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		4 / 4 ASN A 575
SER A 505
LEU A 516
THR A 587
 None
 1.39A 4an2A-4gbfA:
undetectable		 4an2A-4gbfA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		3 / 3 ASP A 426
HIS A 762
LYS A 761
 None
 0.99A 4qzuD-4gbfA:
undetectable		 4qzuD-4gbfA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		4 / 5 GLU A 457
ILE A 558
PHE A 559
VAL A 573
 None
 1.22A 4tvtA-4gbfA:
undetectable		 4tvtA-4gbfA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		6 / 12 THR A 562
GLY A 727
GLY A 687
GLY A 619
ASN A 561
ALA A 413
 None
 1.50A 4uciA-4gbfA:
undetectable		 4uciA-4gbfA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		6 / 12 THR A 562
GLY A 727
GLY A 687
GLY A 619
ASN A 561
ALA A 413
 None
 1.49A 4uciB-4gbfA:
undetectable		 4uciB-4gbfA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		6 / 12 THR A 562
GLY A 727
GLY A 687
GLY A 619
ASN A 561
ALA A 413
 None
 1.46A 4uckA-4gbfA:
undetectable		 4uckA-4gbfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		5 / 11 GLY A 668
ASP A 716
ALA A 702
TYR A 696
VAL A 677
 None
 1.30A 5hw4B-4gbfA:
undetectable		 5hw4B-4gbfA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		4 / 7 THR A 656
PHE A 594
ARG A 651
SER A 617
 None
 1.24A 5uxcA-4gbfA:
3.2		 5uxcA-4gbfA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		4 / 5 VAL A 492
TRP A 494
PRO A 503
THR A 544
 None
 1.49A 6cduA-4gbfA:
undetectable
6cduB-4gbfA:
undetectable		 6cduA-4gbfA:
21.52
6cduB-4gbfA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 4gbf PHIKZ131
(Pseudomonas
virus
phiKZ) 		5 / 12 HIS A 462
SER A 458
TRP A 459
PHE A 421
GLY A 414
 None
 1.31A 6h0gE-4gbfA:
0.0
6h0gF-4gbfA:
undetectable		 6h0gE-4gbfA:
14.08
6h0gF-4gbfA:
5.57