SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		5 / 9 ILE A 262
PHE A 235
GLY A 238
ALA A 179
LEU A 182
 None
 1.14A 1e7bA-4gbjA:
undetectable		 1e7bA-4gbjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 4 ARG A 128
LEU A  13
ASN A  12
VAL A 127
 None
 1.22A 1lqtA-4gbjA:
3.7		 1lqtA-4gbjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1875_0
(FPRA)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 4 ARG A 128
LEU A  13
ASN A  12
VAL A 127
 None
 1.22A 1lqtB-4gbjA:
undetectable		 1lqtB-4gbjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 4 ARG A 128
LEU A  13
ASN A  12
VAL A 127
 None
 1.23A 1lquA-4gbjA:
undetectable		 1lquA-4gbjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1432_0
(FPRA)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 4 ARG A 128
LEU A  13
ASN A  12
VAL A 127
 None
 1.23A 1lquB-4gbjA:
undetectable		 1lquB-4gbjA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 5 TYR A 115
SER A  94
SER A  92
ASN A 168
 None
 1.29A 1yvpA-4gbjA:
4.1		 1yvpA-4gbjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 8 ILE A 146
PHE A 153
TYR A 115
VAL A  65
 None
 0.75A 2w98B-4gbjA:
5.9		 2w98B-4gbjA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		3 / 3 PHE A 121
CYH A 135
PHE A 160
 None
 1.10A 3cr5X-4gbjA:
undetectable		 3cr5X-4gbjA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 8 ILE A 149
LEU A  21
PHE A   7
GLY A  14
 None
 1.00A 3selX-4gbjA:
undetectable		 3selX-4gbjA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		5 / 9 GLY A  60
ALA A 113
GLY A  88
VAL A  62
HIS A 108
 None
 0.93A 4c5lB-4gbjA:
undetectable		 4c5lB-4gbjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 7 GLY A  60
GLY A  88
VAL A  62
HIS A 108
 None
 0.87A 4c5nA-4gbjA:
6.1		 4c5nA-4gbjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 8 GLY A  60
GLY A  88
VAL A  62
HIS A 108
 None
 0.82A 4c5nC-4gbjA:
6.4		 4c5nC-4gbjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		5 / 10 GLY A  60
ALA A 113
GLY A  88
VAL A  62
HIS A 108
 None
 0.91A 4c5nD-4gbjA:
5.2		 4c5nD-4gbjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 8 ARG A 199
ASP A 289
GLU A 187
ARG A 274
 None
 1.40A 4kr4C-4gbjA:
undetectable		 4kr4C-4gbjA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		5 / 12 PHE A   7
ILE A   5
ALA A 142
VAL A  91
ILE A  61
 None
 0.88A 5mlmA-4gbjA:
7.0		 5mlmA-4gbjA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4gbj 6-PHOSPHOGLUCONATE
DEHYDROGENASE
NAD-BINDING
(Dyadobacter
fermentans) 		4 / 4 VAL A 169
LEU A 172
LEU A 244
ASP A  69
 None
 1.26A 5xv7A-4gbjA:
undetectable		 5xv7A-4gbjA:
15.61