SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 5 TYR A 248
LEU A 229
THR A  43
ARG A  46
 None
None
A3P  A 406 ( 3.6A)
None
 1.20A 1i2wA-4gbmA:
undetectable		 1i2wA-4gbmA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		5 / 12 MET A  48
LEU A 221
PHE A 240
GLN A 227
ILE A 275
 None
 1.31A 1xosA-4gbmA:
undetectable		 1xosA-4gbmA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 5 SER A 263
LEU A  85
GLY A  84
ARG A  72
 None
SO4  A 416 (-3.6A)
SO4  A 416 ( 4.9A)
SO4  A 416 (-2.9A)
 0.85A 2j2pA-4gbmA:
undetectable
2j2pB-4gbmA:
undetectable		 2j2pA-4gbmA:
20.06
2j2pB-4gbmA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		5 / 10 LEU A 229
LEU A  45
LEU A  49
ARG A 252
ARG A  46
 None
 1.10A 2xn6A-4gbmA:
undetectable
2xn6B-4gbmA:
undetectable		 2xn6A-4gbmA:
24.47
2xn6B-4gbmA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 7 TYR A 305
TRP A 194
LEU A 303
ASN A 198
 None
None
P6G  A 417 (-4.9A)
None
 1.06A 3k8mA-4gbmA:
undetectable		 3k8mA-4gbmA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 7 TYR A 305
TRP A 194
LEU A 303
ASN A 198
 None
None
P6G  A 417 (-4.9A)
None
 1.02A 3k8mB-4gbmA:
undetectable		 3k8mB-4gbmA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 5 TYR A 137
ILE A 125
LEU A 130
PHE A  33
 CL  A 412 (-4.6A)
None
None
None
 1.04A 3ls4L-4gbmA:
undetectable		 3ls4L-4gbmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 6 GLU A 148
PRO A  29
ARG A  27
GLY A 147
 None
 1.36A 3oxvA-4gbmA:
undetectable		 3oxvA-4gbmA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 7 SER A  57
ALA A  50
PRO A  59
MET A 253
 None
 1.12A 5dzkD-4gbmA:
undetectable
5dzkR-4gbmA:
undetectable		 5dzkD-4gbmA:
20.99
5dzkR-4gbmA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 8 SER A  57
ALA A  50
PRO A  59
MET A 253
 None
 1.13A 5dzkd-4gbmA:
undetectable
5dzkr-4gbmA:
undetectable		 5dzkd-4gbmA:
20.99
5dzkr-4gbmA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		4 / 8 SER A  57
ALA A  50
PRO A  59
MET A 253
 None
 1.14A 5dzkF-4gbmA:
undetectable
5dzkT-4gbmA:
undetectable		 5dzkF-4gbmA:
20.99
5dzkT-4gbmA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		5 / 12 LEU A 236
PHE A 235
LEU A 205
LEU A 208
PHE A  33
 None
 1.19A 5ieoA-4gbmA:
undetectable		 5ieoA-4gbmA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		5 / 12 LEU A 236
PHE A 235
LEU A 205
LEU A 208
PHE A  33
 None
 1.22A 5iepA-4gbmA:
undetectable		 5iepA-4gbmA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4gbm CURM
SULFOTRANSFERASE
(Moorea
producens) 		3 / 3 TYR A 164
ALA A 300
LEU A 292
 None
 0.66A 6d9kF-4gbmA:
3.7		 6d9kF-4gbmA:
17.98