SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4gbo E7
(Thermobifida
fusca) 		3 / 3 ASP A  76
ASP A 120
ASN A  79
 None
None
IOD  A 311 (-4.2A)
 0.85A 2bm9D-4gboA:
undetectable		 2bm9D-4gboA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4gbo E7
(Thermobifida
fusca) 		4 / 5 VAL A 200
VAL A 153
THR A 127
THR A 202
 None
None
IOD  A 314 (-3.5A)
None
 1.23A 3bjwD-4gboA:
undetectable		 3bjwD-4gboA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 4gbo E7
(Thermobifida
fusca) 		3 / 3 ASN A  77
ASP A 120
GLN A 104
 IOD  A 311 (-3.5A)
None
None
 0.79A 3eeyC-4gboA:
undetectable		 3eeyC-4gboA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 4gbo E7
(Thermobifida
fusca) 		3 / 3 ASN A  77
ASP A 120
GLN A 104
 IOD  A 311 (-3.5A)
None
None
 0.81A 3eeyD-4gboA:
undetectable		 3eeyD-4gboA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 4gbo E7
(Thermobifida
fusca) 		3 / 3 ASN A  77
ASP A 120
GLN A 104
 IOD  A 311 (-3.5A)
None
None
 0.80A 3eeyE-4gboA:
undetectable		 3eeyE-4gboA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 4gbo E7
(Thermobifida
fusca) 		4 / 8 GLY A 145
ALA A 146
ASP A 147
THR A 202
 None
 0.66A 3el0A-4gboA:
undetectable		 3el0A-4gboA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4gbo E7
(Thermobifida
fusca) 		4 / 8 TYR A 148
TYR A 152
LEU A 100
TRP A 167
 None
 1.13A 3uzzB-4gboA:
undetectable		 3uzzB-4gboA:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GBO_A_CUA301_0
(E7)		 4gbo E7
(Thermobifida
fusca) 		5 / 5 HIS A  37
ALA A 142
HIS A 144
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
CU  A 301 ( 3.9A)
CU  A 301 (-3.4A)
CU  A 301 ( 4.7A)
None
 0.00A 4gboA-4gboA:
39.6		 4gboA-4gboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GBO_B_CUB301_0
(E7)		 4gbo E7
(Thermobifida
fusca) 		5 / 5 HIS A  37
ALA A 142
HIS A 144
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
CU  A 301 ( 3.9A)
CU  A 301 (-3.4A)
CU  A 301 ( 4.7A)
None
 0.51A 4gboB-4gboA:
37.5		 4gboB-4gboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GBO_B_CUB301_0
(E7)		 4gbo E7
(Thermobifida
fusca) 		4 / 5 HIS A  37
HIS A 208
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
None
CU  A 301 ( 4.7A)
None
 0.75A 4gboB-4gboA:
37.5		 4gboB-4gboA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4gbo E7
(Thermobifida
fusca) 		4 / 5 ALA A 191
VAL A 189
PHE A 221
ILE A 136
 None
 0.97A 5of1A-4gboA:
undetectable		 5of1A-4gboA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4gbo E7
(Thermobifida
fusca) 		4 / 5 ALA A 191
VAL A 189
PHE A 221
ILE A 136
 None
 0.92A 5of1B-4gboA:
undetectable		 5of1B-4gboA:
18.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UIZ_A_CUA301_0
(AA10A)		 4gbo E7
(Thermobifida
fusca) 		5 / 5 HIS A  37
ALA A 142
HIS A 144
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
CU  A 301 ( 3.9A)
CU  A 301 (-3.4A)
CU  A 301 ( 4.7A)
None
 0.06A 5uizA-4gboA:
39.1		 5uizA-4gboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UIZ_B_CUB301_0
(AA10A)		 4gbo E7
(Thermobifida
fusca) 		4 / 4 HIS A  37
HIS A 144
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
CU  A 301 (-3.4A)
CU  A 301 ( 4.7A)
None
 0.55A 5uizB-4gboA:
37.5		 5uizB-4gboA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UIZ_B_CUB301_0
(AA10A)		 4gbo E7
(Thermobifida
fusca) 		4 / 4 HIS A  37
HIS A 208
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
None
CU  A 301 ( 4.7A)
None
 0.77A 5uizB-4gboA:
37.5		 5uizB-4gboA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbo E7
(Thermobifida
fusca) 		4 / 6 GLY A  49
LEU A  52
VAL A 200
PHE A 134
 IOD  A 319 ( 4.4A)
None
None
None
 0.86A 6h7lA-4gboA:
undetectable		 6h7lA-4gboA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbo E7
(Thermobifida
fusca) 		4 / 6 GLY A  49
LEU A  52
VAL A 200
PHE A 134
 IOD  A 319 ( 4.4A)
None
None
None
 0.86A 6h7lB-4gboA:
undetectable		 6h7lB-4gboA:
16.82