SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gcr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_A_EAAA214_1 (GLUTATHIONE S-TRANSFERASE P)	4gcr	GAMMA-B CRYSTALLIN (Bos taurus)	5 / 9	TYR A 151 VAL A 126 GLY A 149 VAL A 132 GLN A 143	None	1.37A	3kmoA-4gcrA: undetectable	3kmoA-4gcrA: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UHX_A_RTZA3009_1 (ALDEHYDE OXIDASE)	4gcr	GAMMA-B CRYSTALLIN (Bos taurus)	4 / 8	ASP A 97 SER A 123 ARG A 152 ARG A 153	None	1.21A	4uhxA-4gcrA: undetectable	4uhxA-4gcrA: 8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_A_ACTA1923_0 (BETA-XYLOSIDASE)	4gcr	GAMMA-B CRYSTALLIN (Bos taurus)	3 / 3	ASP A 64 ARG A 9 TYR A 65	None	1.02A	5a7mA-4gcrA: undetectable	5a7mA-4gcrA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_B_ACTB1924_0 (BETA-XYLOSIDASE)	4gcr	GAMMA-B CRYSTALLIN (Bos taurus)	3 / 3	ASP A 64 ARG A 9 TYR A 65	None	1.01A	5a7mB-4gcrA: undetectable	5a7mB-4gcrA: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_A_ACTA403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	4gcr	GAMMA-B CRYSTALLIN (Bos taurus)	3 / 3	TYR A 62 ASP A 64 GLN A 67	None	0.94A	6g1pA-4gcrA: undetectable	6g1pA-4gcrA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KMO_A_EAAA214_1","GLUTATHIONE S-TRANSFERASE P","4gcr","GAMMA-B CRYSTALLIN","Bos taurus",5,"TYR A 151;VAL A 126;GLY A 149;VAL A 132;GLN A 143","None","1.37A","3kmoA-4gcrA:undetectable","3kmoA-4gcrA:19.82"],["4UHX_A_RTZA3009_1","ALDEHYDE OXIDASE","4gcr","GAMMA-B CRYSTALLIN","Bos taurus",4,"ASP A  97;SER A 123;ARG A 152;ARG A 153","None","1.21A","4uhxA-4gcrA:undetectable","4uhxA-4gcrA:8.30"],["5A7M_A_ACTA1923_0","BETA-XYLOSIDASE","4gcr","GAMMA-B CRYSTALLIN","Bos taurus",3,"ASP A  64;ARG A   9;TYR A  65","None","1.02A","5a7mA-4gcrA:undetectable","5a7mA-4gcrA:15.02"],["5A7M_B_ACTB1924_0","BETA-XYLOSIDASE","4gcr","GAMMA-B CRYSTALLIN","Bos taurus",3,"ASP A  64;ARG A   9;TYR A  65","None","1.01A","5a7mB-4gcrA:undetectable","5a7mB-4gcrA:15.02"],["6G1P_A_ACTA403_0","ADP-RIBOSYLHYDROLASE LIKE 2","4gcr","GAMMA-B CRYSTALLIN","Bos taurus",3,"TYR A  62;ASP A  64;GLN A  67","None","0.94A","6g1pA-4gcrA:undetectable","6g1pA-4gcrA:20.00"]]