SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		3 / 3 GLU A 128
GLN A 136
ARG A 139
 None
 0.91A 2w3bB-4gctA:
undetectable		 2w3bB-4gctA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		4 / 6 ILE A  86
VAL A  89
LEU A  93
LEU A 161
 None
 0.72A 3kp6A-4gctA:
undetectable
3kp6B-4gctA:
1.4		 3kp6A-4gctA:
21.13
3kp6B-4gctA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		4 / 5 PHE A  50
ILE A  30
ASN A   8
PHE A  57
 None
 1.35A 3octA-4gctA:
undetectable		 3octA-4gctA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		5 / 12 THR A 181
PHE A 184
ALA A  95
LEU A  94
ILE A 130
 None
 1.10A 4g1bA-4gctA:
undetectable		 4g1bA-4gctA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		4 / 6 THR A 181
LEU A  68
LEU A 134
GLU A 131
 None
 1.04A 4nc3A-4gctA:
3.1		 4nc3A-4gctA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4gct NUCLEOID OCCLUSION
FACTOR SLMA
(Vibrio
cholerae) 		5 / 12 GLY A  26
SER A  23
ILE A 106
GLY A 109
SER A  28
 None
 0.97A 4obwC-4gctA:
undetectable		 4obwC-4gctA:
23.11