SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gcv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	4gcv	PUTATIVE TRANSCRIPTION PROTEIN (Pseudomonas aeruginosa)	3 / 3	SER A 149 GLU A 150 GLU A 151	None	0.57A	1eqbD-4gcvA: undetectable	1eqbD-4gcvA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	4gcv	PUTATIVE TRANSCRIPTION PROTEIN (Pseudomonas aeruginosa)	3 / 3	SER A 149 GLU A 150 GLU A 151	None	0.57A	1eqbB-4gcvA: undetectable	1eqbB-4gcvA: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XDC_D_DVAD8_0 (GRAMICIDIN A)	4gcv	PUTATIVE TRANSCRIPTION PROTEIN (Pseudomonas aeruginosa)	3 / 3	TRP A 24 VAL A 20 TRP A 23	None	1.06A	2xdcC-4gcvA: undetectable 2xdcD-4gcvA: undetectable	2xdcC-4gcvA: 7.43 2xdcD-4gcvA: 7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y5M_F_DVAF8_0 (VAL-GRAMICIDIN A)	4gcv	PUTATIVE TRANSCRIPTION PROTEIN (Pseudomonas aeruginosa)	3 / 3	TRP A 24 VAL A 20 TRP A 23	None	1.08A	2y5mE-4gcvA: undetectable 2y5mF-4gcvA: undetectable	2y5mE-4gcvA: 7.43 2y5mF-4gcvA: 7.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_FFOA1293_2","SERINE HYDROXYMETHYLTRANSFERASE","4gcv","PUTATIVE TRANSCRIPTION PROTEIN","Pseudomonas aeruginosa",3,"SER A 149;GLU A 150;GLU A 151","None","0.57A","1eqbD-4gcvA:undetectable","1eqbD-4gcvA:17.07"],["1EQB_C_FFOC3293_0","SERINE HYDROXYMETHYLTRANSFERASE","4gcv","PUTATIVE TRANSCRIPTION PROTEIN","Pseudomonas aeruginosa",3,"SER A 149;GLU A 150;GLU A 151","None","0.57A","1eqbB-4gcvA:undetectable","1eqbB-4gcvA:17.07"],["2XDC_D_DVAD8_0","GRAMICIDIN A","4gcv","PUTATIVE TRANSCRIPTION PROTEIN","Pseudomonas aeruginosa",3,"TRP A  24;VAL A  20;TRP A  23","None","1.06A","2xdcC-4gcvA:undetectable;2xdcD-4gcvA:undetectable","2xdcC-4gcvA:7.43;2xdcD-4gcvA:7.43"],["2Y5M_F_DVAF8_0","VAL-GRAMICIDIN A","4gcv","PUTATIVE TRANSCRIPTION PROTEIN","Pseudomonas aeruginosa",3,"TRP A  24;VAL A  20;TRP A  23","None","1.08A","2y5mE-4gcvA:undetectable;2y5mF-4gcvA:undetectable","2y5mE-4gcvA:7.43;2y5mF-4gcvA:7.43"]]