SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 11 LEU A 579
LEU A 577
ALA A 382
MET A 372
LEU A 369
 None
 1.48A 1kt6A-4gdfA:
undetectable		 1kt6A-4gdfA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 10 GLU A 166
LEU A 170
HIS A 192
TYR A 162
PHE A 220
 None
 1.41A 2h21A-4gdfA:
undetectable		 2h21A-4gdfA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 6 LEU A 288
PHE A 327
ILE A 336
ALA A 340
 None
 0.79A 2j5mA-4gdfA:
undetectable		 2j5mA-4gdfA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 7 TYR A 179
VAL A 205
TYR A 211
ILE A 161
 None
 1.21A 2xz5B-4gdfA:
undetectable
2xz5E-4gdfA:
undetectable		 2xz5B-4gdfA:
17.45
2xz5E-4gdfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 8 ILE A 161
TYR A 179
VAL A 205
TYR A 211
 None
 1.20A 2xz5A-4gdfA:
undetectable
2xz5C-4gdfA:
undetectable		 2xz5A-4gdfA:
17.45
2xz5C-4gdfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 8 ILE A 161
TYR A 179
VAL A 205
TYR A 211
 None
 1.18A 2xz5C-4gdfA:
undetectable
2xz5D-4gdfA:
undetectable		 2xz5C-4gdfA:
17.45
2xz5D-4gdfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 7 ILE A 161
TYR A 179
VAL A 205
TYR A 211
 None
 1.19A 2xz5D-4gdfA:
undetectable
2xz5E-4gdfA:
undetectable		 2xz5D-4gdfA:
17.45
2xz5E-4gdfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		3 / 3 GLY A 390
TRP A 393
VAL A 619
 None
 0.76A 3n62B-4gdfA:
undetectable		 3n62B-4gdfA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		3 / 3 GLY A 390
TRP A 393
VAL A 619
 None
 0.75A 3n65B-4gdfA:
undetectable		 3n65B-4gdfA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		3 / 3 GLY A 390
TRP A 393
VAL A 619
 None
 0.76A 3n66B-4gdfA:
undetectable		 3n66B-4gdfA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 4 LEU A 461
GLY A 462
LEU A 509
GLU A 510
 None
 1.06A 3tgvB-4gdfA:
undetectable		 3tgvB-4gdfA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 8 TYR A 314
THR A 280
LEU A 287
MET A 291
 None
 1.28A 3wipG-4gdfA:
undetectable
3wipH-4gdfA:
undetectable		 3wipG-4gdfA:
17.10
3wipH-4gdfA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		4 / 8 LEU A 287
MET A 291
TYR A 314
THR A 280
 None
 1.30A 3wipF-4gdfA:
undetectable
3wipJ-4gdfA:
undetectable		 3wipF-4gdfA:
17.10
3wipJ-4gdfA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		3 / 3 PHE A 197
TYR A 211
TYR A 179
 None
 1.09A 4ffwA-4gdfA:
undetectable		 4ffwA-4gdfA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 10 ARG A 357
VAL A 471
ILE A 525
PHE A 408
ILE A 520
 None
 1.30A 5hw8C-4gdfA:
undetectable
5hw8H-4gdfA:
undetectable		 5hw8C-4gdfA:
13.24
5hw8H-4gdfA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		3 / 3 GLY A 390
TRP A 393
VAL A 619
 None
 0.76A 5vuoB-4gdfA:
undetectable		 5vuoB-4gdfA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 11 VAL A 625
GLY A 624
ALA A 389
SER A 560
LEU A 563
 None
 0.95A 5x6yA-4gdfA:
2.7		 5x6yA-4gdfA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 10 VAL A 625
GLY A 624
ALA A 389
SER A 560
LEU A 563
 None
 0.87A 5x6yB-4gdfA:
2.8		 5x6yB-4gdfA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 4gdf LARGE T ANTIGEN
(Macaca
mulatta
polyomavirus
1) 		5 / 11 VAL A 625
GLY A 624
ALA A 389
SER A 560
LEU A 563
 None
 0.97A 5x6yC-4gdfA:
undetectable		 5x6yC-4gdfA:
20.17