SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gdz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.33A 1zzqA-4gdzA:
undetectable		 1zzqA-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ILE A 127
PHE A  68
VAL A 165
LEU A 154
 GOL  A 201 (-3.7A)
None
None
None
 0.82A 2w98B-4gdzA:
undetectable		 2w98B-4gdzA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 ALA A 163
ASP A 160
LEU A  70
SER A  87
 None
 0.95A 4ot2A-4gdzA:
undetectable		 4ot2A-4gdzA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.30A 5vunA-4gdzA:
undetectable		 5vunA-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.27A 5vunB-4gdzA:
undetectable		 5vunB-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.30A 5vuoB-4gdzA:
undetectable		 5vuoB-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4gdz UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.27A 6auuB-4gdzA:
undetectable		 6auuB-4gdzA:
16.84