SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ge0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUM_H_BEZH1601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 9 ALA A 117
TYR A 142
LEU A 115
GLY A 113
GLY A 129
 None
 1.48A 1rumH-4ge0A:
undetectable
1rumL-4ge0A:
undetectable		 1rumH-4ge0A:
23.14
1rumL-4ge0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 11 LEU A 137
ILE A 107
THR A 157
LEU A 155
VAL A  95
 None
 1.33A 1tw4A-4ge0A:
undetectable		 1tw4A-4ge0A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 GLU A  16
PHE A 167
GLY A 113
GLY A 129
GLY A  78
 None
 1.12A 3tegA-4ge0A:
undetectable		 3tegA-4ge0A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 6 TYR A 144
GLY A 129
VAL A 150
THR A 157
 None
 0.96A 3tj7A-4ge0A:
undetectable
3tj7B-4ge0A:
undetectable		 3tj7A-4ge0A:
22.62
3tj7B-4ge0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 6 TYR A 144
GLY A 129
VAL A 150
THR A 157
 None
 0.95A 3tj7C-4ge0A:
undetectable
3tj7D-4ge0A:
undetectable		 3tj7C-4ge0A:
22.62
3tj7D-4ge0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 6 VAL A 150
THR A 157
TYR A 144
GLY A 129
 None
 0.99A 3tj7C-4ge0A:
undetectable
3tj7D-4ge0A:
undetectable		 3tj7C-4ge0A:
22.62
3tj7D-4ge0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY A  82
ASP A  13
GLY A  78
CYH A 111
 None
 0.88A 4c5nA-4ge0A:
undetectable		 4c5nA-4ge0A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		3 / 3 LYS A 105
LYS A 102
PRO A 103
 None
 1.16A 4dv1L-4ge0A:
undetectable		 4dv1L-4ge0A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 137
VAL A 133
ALA A 112
ALA A 117
THR A 116
 None
 1.20A 4fiaA-4ge0A:
undetectable		 4fiaA-4ge0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 137
VAL A 133
ALA A 112
ALA A 117
THR A 116
 None
 1.20A 4fiaA-4ge0A:
undetectable		 4fiaA-4ge0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 ILE A  23
LEU A 172
ALA A 183
SER A 187
LEU A 188
 None
 1.04A 4m11B-4ge0A:
undetectable		 4m11B-4ge0A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A   6
VAL A  44
MET A  46
MET A  52
ILE A  61
 None
 1.36A 4oktA-4ge0A:
undetectable		 4oktA-4ge0A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 11 SER A 132
GLY A  78
GLY A  79
LEU A  86
ILE A 110
 None
 1.17A 4pghA-4ge0A:
undetectable		 4pghA-4ge0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 SER A 132
GLY A  78
GLY A  79
LEU A  86
ILE A 110
 None
 1.15A 4pghD-4ge0A:
2.9		 4pghD-4ge0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 12 MET A  52
GLY A  11
ALA A  83
ASP A  10
ALA A   9
 None
 1.16A 5kvaB-4ge0A:
2.4		 5kvaB-4ge0A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		5 / 10 LEU A 155
LEU A 171
ILE A 127
SER A 158
GLY A 129
 None
 1.22A 6dm0B-4ge0A:
4.0
6dm0C-4ge0A:
3.9		 6dm0B-4ge0A:
15.90
6dm0C-4ge0A:
15.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		8 / 10 GLU A  16
GLY A  78
GLY A  79
ILE A 110
ALA A 112
PRO A 114
HIS A 130
GLY A 160
 None
 0.31A 6e5zA-4ge0A:
28.7		 6e5zA-4ge0A:
33.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 8 HIS A 130
GLU A  16
ASP A  13
GLU A  14
 None
 1.17A 6mn4C-4ge0A:
undetectable		 6mn4C-4ge0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 4ge0 UNCHARACTERIZED
PROTEIN C22E12.03C
(Schizosaccharomy
ces
pombe) 		4 / 6 THR A 163
LEU A 166
THR A 128
LEU A 171
 None
 1.09A 6mvxA-4ge0A:
undetectable
6mvxB-4ge0A:
undetectable
6mvxC-4ge0A:
undetectable		 6mvxA-4ge0A:
23.08
6mvxB-4ge0A:
23.08
6mvxC-4ge0A:
23.08