SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gf4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	4gf4	PORIN B (Pseudomonas putida)	4 / 5	VAL A 192 GLY A 193 VAL A 180 TRP A 120	C8E A 503 (-4.2A) C8E A 503 ( 4.6A) C8E A 503 ( 4.9A) None	1.34A	1tkqB-4gf4A: undetectable	1tkqB-4gf4A: 2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR)	4gf4	PORIN B (Pseudomonas putida)	5 / 12	LEU A 295 LEU A 319 VAL A 320 VAL A 284 GLN A 283	None C8E A 501 ( 4.4A) None C8E A 501 ( 4.8A) None	1.32A	3m7rA-4gf4A: undetectable	3m7rA-4gf4A: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HXI_B_ACTB706_0 (SUCCINYL-COA LIGASE (ADP-FORMING) SUBUNIT ALPHA)	4gf4	PORIN B (Pseudomonas putida)	4 / 5	HIS A 341 VAL A 311 ARG A 339 PHE A 301	None	1.26A	6hxiB-4gf4A: undetectable	6hxiB-4gf4A: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NJ9_K_SAMK500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	4gf4	PORIN B (Pseudomonas putida)	3 / 3	THR A 302 GLU A 236 ASN A 144	None	0.91A	6nj9K-4gf4A: undetectable	6nj9K-4gf4A: 22.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","4gf4","PORIN B","Pseudomonas putida",4,"VAL A 192;GLY A 193;VAL A 180;TRP A 120","C8E A 503 (-4.2A);C8E A 503 ( 4.6A);C8E A 503 ( 4.9A);None","1.34A","1tkqB-4gf4A:undetectable","1tkqB-4gf4A:2.98"],["3M7R_A_VDXA425_1","VITAMIN D3 RECEPTOR","4gf4","PORIN B","Pseudomonas putida",5,"LEU A 295;LEU A 319;VAL A 320;VAL A 284;GLN A 283","None;C8E A 501 ( 4.4A);None;C8E A 501 ( 4.8A);None","1.32A","3m7rA-4gf4A:undetectable","3m7rA-4gf4A:21.17"],["6HXI_B_ACTB706_0","SUCCINYL-COA LIGASE (ADP-FORMING) SUBUNIT ALPHA","4gf4","PORIN B","Pseudomonas putida",4,"HIS A 341;VAL A 311;ARG A 339;PHE A 301","None","1.26A","6hxiB-4gf4A:undetectable","6hxiB-4gf4A:20.21"],["6NJ9_K_SAMK500_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","4gf4","PORIN B","Pseudomonas putida",3,"THR A 302;GLU A 236;ASN A 144","None","0.91A","6nj9K-4gf4A:undetectable","6nj9K-4gf4A:22.46"]]