SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ghn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ASP A 197
ARG A 200
ILE A 159
 None
 0.74A 1a4gB-4ghnA:
undetectable		 1a4gB-4ghnA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 6 THR A 118
SER A 109
GLY A 101
ILE A 103
 None
 0.90A 1gtnD-4ghnA:
undetectable
1gtnE-4ghnA:
undetectable		 1gtnD-4ghnA:
11.20
1gtnE-4ghnA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 9 GLY A 278
GLY A 279
SER A 327
ALA A 328
HIS A 115
 None
 0.90A 2aceA-4ghnA:
undetectable		 2aceA-4ghnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.19A 3abmA-4ghnA:
undetectable
3abmC-4ghnA:
undetectable
3abmP-4ghnA:
undetectable		 3abmA-4ghnA:
21.01
3abmC-4ghnA:
20.61
3abmP-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 MET A 282
ASN A 280
GLY A 279
MET A 306
CYH A 288
 None
 1.37A 3cldB-4ghnA:
undetectable		 3cldB-4ghnA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 10 MET A 282
SER A 281
ASP A 335
SER A 331
GLY A 354
 None
 1.45A 3lsfB-4ghnA:
undetectable
3lsfE-4ghnA:
0.0		 3lsfB-4ghnA:
23.41
3lsfE-4ghnA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 9 MET A 248
LEU A 319
LEU A 320
THR A 244
VAL A 231
 None
 1.35A 3ozkA-4ghnA:
undetectable		 3ozkA-4ghnA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.22A 3wg7A-4ghnA:
undetectable
3wg7C-4ghnA:
undetectable
3wg7P-4ghnA:
undetectable		 3wg7A-4ghnA:
21.01
3wg7C-4ghnA:
20.61
3wg7P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 MET A 282
ASN A 280
GLY A 279
MET A 306
CYH A 288
 None
 1.31A 5nfpA-4ghnA:
undetectable		 5nfpA-4ghnA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 7 GLY A 350
HIS A 182
HIS A 115
ASP A 352
 None
 1.06A 5no9D-4ghnA:
undetectable		 5no9D-4ghnA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 LYS A 302
LYS A 380
SER A 378
 None
 1.44A 5odiA-4ghnA:
undetectable		 5odiA-4ghnA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.22A 5z84A-4ghnA:
undetectable
5z84C-4ghnA:
undetectable
5z84P-4ghnA:
undetectable		 5z84A-4ghnA:
21.01
5z84C-4ghnA:
20.61
5z84P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 7 LEU A  72
HIS A 298
ASP A 352
THR A 353
 None
 1.24A 5z84C-4ghnA:
undetectable
5z84N-4ghnA:
undetectable
5z84P-4ghnA:
undetectable		 5z84C-4ghnA:
20.61
5z84N-4ghnA:
21.01
5z84P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.22A 5z85A-4ghnA:
undetectable
5z85C-4ghnA:
undetectable
5z85P-4ghnA:
undetectable		 5z85A-4ghnA:
21.01
5z85C-4ghnA:
20.61
5z85P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 7 LEU A  72
HIS A 298
ASP A 352
THR A 353
 None
 1.22A 5z85C-4ghnA:
undetectable
5z85N-4ghnA:
undetectable
5z85P-4ghnA:
undetectable		 5z85C-4ghnA:
20.61
5z85N-4ghnA:
21.01
5z85P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.21A 5z86A-4ghnA:
undetectable
5z86C-4ghnA:
undetectable
5z86P-4ghnA:
undetectable		 5z86A-4ghnA:
21.01
5z86C-4ghnA:
20.61
5z86P-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.22A 5zcoA-4ghnA:
undetectable
5zcoC-4ghnA:
undetectable
5zcoP-4ghnA:
undetectable		 5zcoA-4ghnA:
21.01
5zcoC-4ghnA:
20.61
5zcoP-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.20A 5zcpA-4ghnA:
undetectable
5zcpC-4ghnA:
undetectable
5zcpP-4ghnA:
undetectable		 5zcpA-4ghnA:
21.01
5zcpC-4ghnA:
20.61
5zcpP-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 LEU A  72
HIS A 298
ASP A 352
THR A 353
 None
 1.21A 5zcpC-4ghnA:
undetectable
5zcpN-4ghnA:
undetectable
5zcpP-4ghnA:
undetectable		 5zcpC-4ghnA:
20.61
5zcpN-4ghnA:
21.01
5zcpP-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 HIS A 298
ASP A 352
THR A 353
LEU A  72
 None
 1.22A 5zcqA-4ghnA:
undetectable
5zcqC-4ghnA:
undetectable
5zcqP-4ghnA:
undetectable		 5zcqA-4ghnA:
21.01
5zcqC-4ghnA:
20.61
5zcqP-4ghnA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 5 ARG A  90
ALA A  94
TYR A 100
ILE A  45
 GOL  A 501 (-3.8A)
None
None
None
 1.18A 6f6sA-4ghnA:
undetectable
6f6sB-4ghnA:
undetectable		 6f6sA-4ghnA:
12.91
6f6sB-4ghnA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4ghn UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 4 ASP A 352
SER A 281
SER A 331
ASN A 355
 None
 1.18A 6iblB-4ghnA:
0.0		 6iblB-4ghnA:
21.10