SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 7 ILE A 186
THR A 174
ILE A 303
GLY A 132
 None
 0.77A 2v0mB-4gijA:
undetectable		 2v0mB-4gijA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 ILE A  55
ALA A  63
PHE A 128
ILE A  34
VAL A  51
 None
 1.12A 2w3aA-4gijA:
undetectable		 2w3aA-4gijA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 7 LEU A 178
ALA A 165
GLY A 134
PHE A 181
 None
None
SO4  A 400 ( 4.4A)
None
 0.98A 2wq5A-4gijA:
0.7		 2wq5A-4gijA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 7 PHE A 128
ILE A   6
LEU A  99
THR A 156
 None
 1.21A 3nxuA-4gijA:
undetectable		 3nxuA-4gijA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		6 / 12 LEU A 185
ASN A 296
ALA A 165
ALA A 195
LEU A 171
LEU A 153
 None
 1.48A 3p5nB-4gijA:
undetectable		 3p5nB-4gijA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 10 ILE A  81
GLU A  79
ILE A  49
GLU A  53
ARG A  56
 None
 0.94A 3u6tA-4gijA:
undetectable		 3u6tA-4gijA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB802_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 12 PHE A 203
SER A 167
ASP A 170
ASP A 204
PRO A 202
 None
 1.46A 3v8vB-4gijA:
undetectable		 3v8vB-4gijA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 8 SER A 201
GLU A 176
TYR A 177
GLY A 135
 None
 0.87A 4fgzA-4gijA:
undetectable
4fgzB-4gijA:
undetectable		 4fgzA-4gijA:
20.00
4fgzB-4gijA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 12 LEU A 173
GLY A 135
VAL A 232
LEU A 178
VAL A 183
 None
 0.96A 4gc9A-4gijA:
2.2		 4gc9A-4gijA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 6 LEU A 299
ASN A 296
MET A 219
VAL A 113
 None
 1.10A 4okbA-4gijA:
undetectable		 4okbA-4gijA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qvlV-4gijA:
undetectable
4qvlb-4gijA:
undetectable		 4qvlV-4gijA:
23.37
4qvlb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qvlH-4gijA:
undetectable
4qvlN-4gijA:
undetectable		 4qvlH-4gijA:
23.37
4qvlN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 4qvmV-4gijA:
undetectable
4qvmb-4gijA:
undetectable		 4qvmV-4gijA:
23.37
4qvmb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 4qvmH-4gijA:
undetectable
4qvmN-4gijA:
undetectable		 4qvmH-4gijA:
23.37
4qvmN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 4qvpV-4gijA:
undetectable
4qvpb-4gijA:
undetectable		 4qvpV-4gijA:
23.37
4qvpb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 4qvpH-4gijA:
undetectable
4qvpN-4gijA:
undetectable		 4qvpH-4gijA:
23.37
4qvpN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 4qvwV-4gijA:
undetectable
4qvwb-4gijA:
undetectable		 4qvwV-4gijA:
23.37
4qvwb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qvwH-4gijA:
undetectable
4qvwN-4gijA:
undetectable		 4qvwH-4gijA:
23.37
4qvwN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.27A 4qw0V-4gijA:
undetectable
4qw0b-4gijA:
undetectable		 4qw0V-4gijA:
23.37
4qw0b-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qw0H-4gijA:
undetectable
4qw0N-4gijA:
undetectable		 4qw0H-4gijA:
23.37
4qw0N-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.24A 4qw1V-4gijA:
undetectable
4qw1b-4gijA:
undetectable		 4qw1V-4gijA:
23.37
4qw1b-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qw1H-4gijA:
undetectable
4qw1N-4gijA:
undetectable		 4qw1H-4gijA:
23.37
4qw1N-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qw3V-4gijA:
undetectable
4qw3b-4gijA:
undetectable		 4qw3V-4gijA:
23.37
4qw3b-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.25A 4qw3H-4gijA:
undetectable
4qw3N-4gijA:
undetectable		 4qw3H-4gijA:
23.37
4qw3N-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		4 / 5 SER A 115
ARG A  96
LEU A  99
ASP A  98
 None
 1.36A 4xdtA-4gijA:
undetectable		 4xdtA-4gijA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 12 VAL A  91
SER A  32
LEU A  84
VAL A 102
LEU A  76
 None
 1.00A 4y8wC-4gijA:
undetectable		 4y8wC-4gijA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A  32
THR A  64
SER A  77
GLU A  79
GLY A  85
 None
 1.18A 4zjoD-4gijA:
undetectable		 4zjoD-4gijA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.18A 5bxnV-4gijA:
undetectable
5bxnb-4gijA:
undetectable		 5bxnV-4gijA:
23.08
5bxnb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.20A 5bxnH-4gijA:
undetectable
5bxnN-4gijA:
undetectable		 5bxnH-4gijA:
23.08
5bxnN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.27A 5cz7H-4gijA:
undetectable
5cz7N-4gijA:
undetectable		 5cz7H-4gijA:
23.37
5cz7N-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.27A 5d0xV-4gijA:
undetectable
5d0xb-4gijA:
undetectable		 5d0xV-4gijA:
23.37
5d0xb-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 5d0xH-4gijA:
undetectable
5d0xN-4gijA:
undetectable		 5d0xH-4gijA:
23.37
5d0xN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 12 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.26A 5l5zH-4gijA:
undetectable
5l5zN-4gijA:
undetectable		 5l5zH-4gijA:
23.37
5l5zN-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.23A 5l66V-4gijA:
undetectable
5l66b-4gijA:
undetectable		 5l66V-4gijA:
23.37
5l66b-4gijA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4gij PSEUDOURIDINE-5'-PHO
SPHATE GLYCOSIDASE
(Escherichia
coli) 		5 / 11 SER A 201
THR A 174
THR A 175
GLY A 164
ALA A 195
 None
 1.21A 5l66H-4gijA:
undetectable
5l66N-4gijA:
undetectable		 5l66H-4gijA:
23.37
5l66N-4gijA:
20.94