SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gio'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 10 LEU A 102
VAL A  29
VAL A  71
TYR A  69
LEU A  59
 None
 1.04A 1fkoA-4gioA:
undetectable		 1fkoA-4gioA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		3 / 3 LEU A  35
PRO A  36
LEU A  31
 BR  A 201 ( 4.8A)
None
None
 0.57A 2po7B-4gioA:
undetectable		 2po7B-4gioA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		3 / 3 LEU A  35
PRO A  36
LEU A  31
 BR  A 201 ( 4.8A)
None
None
 0.42A 3hcrA-4gioA:
undetectable		 3hcrA-4gioA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 4 LEU A  35
PRO A  36
LEU A  31
ILE A 118
 BR  A 201 ( 4.8A)
None
None
None
 0.96A 4f4dB-4gioA:
undetectable		 4f4dB-4gioA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 12 VAL A  84
ASP A  83
SER A 107
THR A  28
ARG A 110
 None
 1.43A 5m50B-4gioA:
undetectable		 5m50B-4gioA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4gio PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 12 VAL A  84
ASP A  83
SER A 107
THR A  28
ARG A 110
 None
 1.31A 5m54B-4gioA:
undetectable		 5m54B-4gioA:
15.29