SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4gip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 4gip FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5) 		4 / 6 ALA D 455
LYS D 458
ASP D 462
ALA D 463
 None
 0.36A 1iwhA-4gipD:
undetectable		 1iwhA-4gipD:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 4gip FUSION GLYCOPROTEIN
F2
FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5;
Mammalian
rubulavirus
5) 		5 / 12 LEU D 413
ILE D 405
ILE A  31
PRO A  32
PHE D 365
 None
 0.94A 2ygqA-4gipD:
undetectable		 2ygqA-4gipD:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 11 VAL D 175
ILE D 180
ILE A  69
LEU D 196
ILE D 172
 None
 1.05A 3clbA-4gipD:
undetectable		 3clbA-4gipD:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 12 VAL D 175
ILE D 180
ILE A  69
LEU D 196
ILE D 172
 None
 1.04A 3clbC-4gipD:
undetectable		 3clbC-4gipD:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 10 VAL D 175
ILE D 180
ILE A  69
LEU D 196
ILE D 172
 None
 1.06A 3hbbA-4gipD:
undetectable		 3hbbA-4gipD:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 11 VAL D 175
ILE D 180
ILE A  69
LEU D 196
ILE D 172
 None
 1.00A 3hbbC-4gipD:
undetectable		 3hbbC-4gipD:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4gip FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5) 		3 / 3 LEU D 305
PRO D 306
LEU D 289
 None
 0.55A 3hcrA-4gipD:
undetectable		 3hcrA-4gipD:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		4 / 8 TYR A  40
ASN D 336
ASP D 337
LEU A  38
 None
 1.09A 4f8hB-4gipA:
undetectable
4f8hC-4gipA:
undetectable		 4f8hB-4gipA:
16.85
4f8hC-4gipA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		4 / 8 LEU A  38
TYR A  40
ASN D 336
ASP D 337
 None
 1.11A 4f8hA-4gipA:
undetectable
4f8hE-4gipA:
undetectable		 4f8hA-4gipA:
16.85
4f8hE-4gipA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		3 / 3 LEU A  94
ARG A  91
MET D 269
 None
 0.97A 4m11C-4gipA:
undetectable		 4m11C-4gipA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 4gip FUSION GLYCOPROTEIN
F2
FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5;
Mammalian
rubulavirus
5) 		5 / 12 ALA D 215
LEU A  80
ILE D 206
LEU D 227
ILE D 219
 None
 1.13A 4nx7A-4gipD:
undetectable		 4nx7A-4gipD:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		4 / 6 LEU D 255
THR D 163
LEU D 275
SER A  45
 None
 1.03A 4pwjA-4gipD:
undetectable		 4pwjA-4gipD:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 4gip FUSION GLYCOPROTEIN
F2
FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5;
Mammalian
rubulavirus
5) 		4 / 4 ILE D 287
ASN A  34
ILE D 326
VAL D 331
 None
 1.12A 4uy87-4gipD:
undetectable		 4uy87-4gipD:
4.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 12 VAL D 402
LEU D 305
LEU A  25
LEU D 289
THR D 307
 None
 1.20A 5hnwB-4gipD:
undetectable		 5hnwB-4gipD:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 4gip FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5) 		5 / 10 ILE D 206
LEU D 203
ILE D 259
LEU D 262
LEU D 224
 None
 1.17A 5ienB-4gipD:
undetectable		 5ienB-4gipD:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 12 LEU A  79
TYR D 199
LEU D 228
LEU D 224
PHE D 207
 None
 1.27A 5ieoA-4gipA:
undetectable		 5ieoA-4gipA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4gip FUSION GLYCOPROTEIN
F1
FUSION GLYCOPROTEIN
F2
(Mammalian
rubulavirus
5) 		5 / 11 ILE D 273
VAL D 165
VAL A  50
MET D 269
LEU D 227
 None
 1.28A 5jkwA-4gipD:
undetectable		 5jkwA-4gipD:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4gip FUSION GLYCOPROTEIN
F2
FUSION GLYCOPROTEIN
F1
(Mammalian
rubulavirus
5;
Mammalian
rubulavirus
5) 		4 / 6 LEU D 227
TYR A  72
THR A  77
LEU A  80
 None
 0.65A 5x1fA-4gipD:
undetectable
5x1fJ-4gipD:
undetectable		 5x1fA-4gipD:
20.57
5x1fJ-4gipD:
7.58